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*- is an abnormally high level of uric acid in

the blood.
* - peak incidence occurs in patients 30 to
50 years old.
*- much common in men than women.

*Uric acid is produced during the


breakdown of purines, which are found in
certain foods and are also formed by your
body.
Causes:

 Increased production of uric acid.

 Decreased excretion of uric acid

 Mixed of both
Normal Values of Uric Acid:

Female- 2.4-6.0mg/dl

Male- 3.4- 7.0mg/dl


• High level of uric acid
• Inflammation of a single joint (big toe, ankle or
finger joint)
• Fever, chills, fatigue (cancer patients)
• Other kidney/urination problems
Lab Testing and Examinations:

• Serum uric acid test


• CBC count
• Evaluation of electrolytes, BUN and serum creatinine
levels
• Liver function tests
• Serum glucose level
• Lipid profile
• Calcium and phosphate levels
• Thyroid-stimulating hormone levels
• Urinary uric acid excretion
Imaging Studies

• X-ray (conducted on patients who may


have joint swelling or gout)

• Renal sonogram (performed on patients


with symptomatic hyperuricemia to
evaluate the kidneys)
• Nonsteroidal Anti-inflammatory Drugs (NSAID’s)
e.g: Celecoxib, Ibuprofen, Diclofenac

• Corticosteroids
e.g: Hydrocortisone, Prednisone, Prednisolone

• Oral Colchicine

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