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  • Infection in Hematology Malignancies

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    Dany Ramdhani
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    Patients with hematological malignancies have weakened immune systems, making them susceptible to infections. Herpesviridae infections in particular pose risks, as this family of viruses can lie dormant and recur. The Herpesviridae are a family of dsDNA viruses with icosahedral capsids and tegument layers between the capsid and envelope. They have glycoprotein spikes and come in 8 human serotypes that can establish latent infections and periodically reactivate, posing challenges for immunocompromised hematology patients.

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    Patients with hematological malignancies have weakened immune systems, making them susceptible to infections. Herpesviridae infections in particular pose risks, as this family of viruses can lie dormant and recur. The Herpesviridae are a family of dsDNA viruses with icosahedral capsids and tegument layers between the capsid and envelope. They have glycoprotein spikes and come in 8 human serotypes that can establish latent infections and periodically reactivate, posing challenges for immunocompromised hematology patients.

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    5 views73 pages

    Infection in Hematology Malignancies

    Uploaded by

    Dany Ramdhani
    Patients with hematological malignancies have weakened immune systems, making them susceptible to infections. Herpesviridae infections in particular pose risks, as this family of viruses can lie dormant and recur. The Herpesviridae are a family of dsDNA viruses with icosahedral capsids and tegument layers between the capsid and envelope. They have glycoprotein spikes and come in 8 human serotypes that can establish latent infections and periodically reactivate, posing challenges for immunocompromised hematology patients.

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    Infection in Hematology Malignancies

    M Erwin Indrakusuma
    FK Universitas Gunung jati/RSUD Waled Kab Cirebon
    A.Safdar and D. Amstrong
    Clin. Infectious Disease, 2011 : 53 Imunocompromised Host
    HSV
    Infections
    HERPESVIRIDAE

    • ds DNA
    • Icosahedral
    • Asymmetrical tegument
    between capsid and envelope
    • Enveloped
    • Glycoprotein spikes
    • 8 human serotypes
    • Latent, recurring infections
    TERIMA KASIH

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