A physiological signal-based

method for early mental-stress

detection.

By: Likun Xia , Aamir Saeed Malik , Ahmad Rauf

Subhani
Reference: www.sciencedirect.com
ABSTRACT
The early detection of mental stress is critical for efficient clinical treatment. As compared
with traditional approaches, the automatic methods presented in literature have shown
significance and effectiveness in terms of diagnosis speed. Unfortunately, the majority of
them mainly focus on accuracy rather than predictions for treatment efficacy. This may
result in the development of methods that are less robust and accurate, which is
unsuitable for clinical purposes. In this study, we propose a comprehensive framework for
the early detection of mental stress by analysing variations in both electroencephalogram
(EEG) and electrocardiogram (ECG) signals from 22 male subjects (mean age: 22.54 ± 1.53
years). The significant contribution of this paper is that the presented framework is capable
of performing predictions for treatment efficacy, which is achieved by defining four stress
levels and creating models for the individual level. The experimental results indicate that
the framework has realized an accuracy, a sensitivity, and a specificity of 79.54%, 81%, and
78%, respectively. Moreover, the results indicate significant neurophysiological differences
between the stress and control (stress-free) conditions at the individual level.
 A Micro-Power EEG Acquisition SoC With
Integrated Feature Extraction Processor for a
Chronic Seizure Detection System.

By: Naveen Verma, Ali Shoeb, Jose Bohorquez, Joel Dawson, John Guttag,
Anantha Chandrakasan
Reference: ieeexplore.ieee.org
ABSTRACT
This paper presents a low-power SoC that performs EEG acquisition and feature extraction
required for continuous detection of seizure onset in epilepsy patients. The SoC corresponds to
one EEG channel, and, depending on the patient, up to 18 channels may be worn to detect
seizures as part of a chronic treatment system. The SoC integrates an instrumentation
amplifier, ADC, and digital processor that streams features-vectors to a central device where
seizure detection is performed via a machine-learning classifier. The instrumentation-amplifier
uses chopper-stabilization in a topology that achieves high input-impedance and rejects large
electrode-offsets while operating at 1 V; the ADC employs power-gating for low energy-per-
conversion while using static-biasing for comparator precision; the EEG feature extraction
processor employs low-power hardware whose parameters are determined through validation
via patient data. The integration of sensing and local processing lowers system power by 14× by
reducing the rate of wireless EEG data transmission. Feature vectors are derived at a rate of 0.5
Hz, and the complete one-channel SoC operates from a 1 V supply, consuming 9 ¿ J per feature
vector.