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PANEL SESSION

THE 4TH INTERNATIONAL CONFERENCE


ON APPLIED SCIENCE AND HEALTH
Science for the mankind: translation research results into policy and practices
23-24 July 2019 | Mahidol University | Thailand

ANTIMICROBIAL ACTIVITY OF KERSEN


(MUNTINGIA CALABURA L.) LEAVES: A
SYSTEMATIC REVIEW

Diah Ulfa Hidayati / diahulfa16@gmail.com


Master of Applied Science in Midwifery
Poltekkes Kemenkes Semarang, Indonesia
Outline

• Background
• Objective
• Methods
• Results
• Conclusion

The 4TH ICASH, 23-24 July 2019, Mahidol University, Thailand | www.INSCHOOL.id
Background

• In 2015, about 830 women died during pregnancy and


childbirth. One of the primary causes is infections.
• Antibiotic resistance has increased.
• About 80% of people in the worldwide depend on the
traditional medicine for their basic healthcare.
Con’t..

Muntingia Calabura L. leaves contains


many types of flavonoid. A study
indicated the presence of flavonoids in
the leaves is typically involved in
antimicrobial activities.
Objective

To gather all information related to antibacterial activity of


Muntingia calabura leaves and present them as a
comprehensive and systematic review article.
Methods

• Records identified
through database
Identification searching (n = 736)

• Articles screened base of title, abstract and


keywords (n=36)
Screening

• Full-text articles assessed for eligibility (n = 9)


Eligibility

• Selection studies (n = 9)
Included
Results

Extraction Methods Antibacterial Test

1, 11%

2, 22%

8, 89% 7, 78%

Maceration Nanoparticles Diffusion Dilution


Con’t..
Microorganism
8
7
6
5
4
3
2
1
0
A. Niger B. Cereus B. Subtilis C. Albicans E. Coli P. Aeruginosa S. Aureus Others
Microorganism
Con’t..

All studies showed that Muntingia calabura leaves had


flavonoids. Flavonoids can act as antibacterial. The most
widely used bacteria is S. Aureus. The results of antimicrobial
tests in each study showed several similarities and
differences.
Conclusion

From 9 studies, antimicrobial test for Muntingia calabura leaves


was carried out on 18 types of microorganisms. Every study
proves that Muntingia Calabura leaves show an antimicrobial
effect on several different microorganisms. Therefore, this review
paper is presented to help guide researchers to plan their future
studies related to this plant for preventing the infectious
diseases.
THANK YOU

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