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Ergo Genic
Ergo Genic
Nutritional aids
Pharmacological aids
Physiological aids
Psychological aids
Mechanical or biomechanical aids
Alcohol
Classification: Physiologic or
pharmacologic
Theory: All types of NOS produce NO from
arginine with the aid of molecular oxygen
and NADPH.
NO diffuses freely across cell membranes.
Intracellular messenger within adipocytes
Insulin - stimulated glucose uptake dependent
on NO synthesis
NO: suppress leptin secretion (leptin increases
eNOS)
Suppresses lipolysis
There are so many other molecules with
which it can interact, that it is quickly
consumed close to where it is synthesized.
NO relaxes the smooth muscle in the walls
of the arterioles.
At each systole, the endothelial cells that
line the blood vessels release a puff of NO.
This diffuses into the underlying smooth muscle
cells causing them to relax and thus permit the
surge of blood to pass through easily.
Mice whose genes for the NO synthase found in
endothelial cells (eNOS) has been "knocked out"
suffer from hypertension.
The erection of the penis during sexual
excitation is mediated by NO released from
nerve endings close to the blood vessels of the
penis.
Relaxation of these vessels causes blood to pool
in the blood sinuses producing an erection.
Bodybuilders take it b/c increased blood
flow will serve to deliver more nutrients to
muscles
And, NO acts to reduce inflammation
Safety: inhibiting NOS decreases tumor
grow growth, not sure if it is absorbed from
the gut
Legal/Ethical: ???
Recommendations: Wait for more data