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GROUP ASSIGNMENT
LEARNING OUTCOME
Students will able to

1. Describe glossitis, stomatitis and leukoplakia

characteristic per definition
2. Describe the etiology, pathophysiology and
predisposition of the diseases
3. Describe the symptoms and clinical
manifestation of the diseases
4. Identified the disease’s characteristic and able to
determine the diagnose within the differential
5. Describe the initial procedure of treatment
Oral mucosa appearance/Oral Lessions
:
WHITE APPEARANCE RED APPEARANCE

1. Production of keratin 1. Reduction in the number of

increase epithealial cells
2. Abnormal thickening of 2. Increased vascularization
stratum spinosum (dilatation/proliferation of
3. Extracelluler accumulation vessels)
of fluid in the epithelium 3. Immune pathogenesis
4. Pseudomembranes
production by microbes,
particularly fungi
GLOSSITIS

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Glossitis’ Types

Atrophic glossitis Median

rhomboid
glossitis

Benign migratory Herpetic

Glossitis/geographic geometric
tongue glossitis
Differential Diagnosis

Strawberry Fissure Burning Oral

mouth squamous cell
Tongue Tongue carcinoma
syndrome
Initial Treatment
• Symptomatic - analgesic
• Antifungal
• Antibiotic
• Steroid
• Supplements
• Avoid irritants
STOMATITIS

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 Inflammatory changes of oral mucose with or
DEFINITION without ulceration
(mucositis if it caused by irradiation or
chemotherapy)

Poor OH
ETIOLOGY Denture (denture stomatitis)
Infection (GO, HSV, fungal, etc)
AB usage (e.g azathioprine)
Traumatic cause/irritants
Hormonal
Allergy
Psychological effect
Nutritional deficiencies
Malignancy ;
Manifestation of systemic condition

Lesion, ulcer
CLINICAL Redness ; reddish edge
PRESENTATION Painful
Recurrent (in some cases)
With or without induration
No fever related
Stomatitis Type’s
(Due to etiology)
• Aphthous Stomatitis
• Traumatic Stomatitis/ Traumatic Ulcer
• Stomatitis Nicotina
• Stomatitis Allergica
• Denture Stomatitis
• Recurrent Aphthous Stomatitis (RAS)
• Gonoccocal Stomatitis
• Angular Stomatitis/Cheilitis
• Etc (Symptom of squamous cell carcinoma)
 Denture Multiple Minor Angular
Stomatitis Aphthous Cheilitis/Stomati
Stomatitis tis
 Differential Diagnosis

1. Crohn’s Disease

2. Herpes Labialis

3. Behcet’s Syndrome
(RAS, uveitis/conjunctivitis, genital ulcer

4. HIV infection
Initial Treatment
• Analgesic
• Local application of steroid
• Antibiotic
• Antifungal
• Supplement
• Increasing OH
• Avoid irritants
LEUKOPLAKIA

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 • Predominantly white lesion/patch/plaque
DEFINITION • Condition of the oral mucosa that clinically and
hispathologically can’t be recognized as any
other well-defined lesion/condition
• Premalignant

Exact etiology remain unknown but common in

ETIOLOGY smoker and smokeless tobacco
Tobacco
PREDISPOSING Alcohol
FACTOR Infection
Candida albicans
HPV (but not seem to play important role)

White patch/plaque
CLINICAL Burning sensation or asymtomatic
PRESENTATION Sometimes painful and itchy
Can’t be scraped
Following by limfatic enlargement in same cases
Leukoplakia Type’s
Homogenous Hairy Common in
Leukoplakia Leukoplakia patient with
AIDS

Nonhomogenou Erythro-
s Leukoplakia leukoplakia
Differential Diagnosis

Lichen Planus Oral Candidiasis Hairy Tongue

Initial Treatment
• Eliminate predisposing factor
• A biopsy
• Surgical excision
• Should be followed-up at intervals 3 – 6 mo,
lifelong
• Isaac van del Waal. Atlas of Oral Diseases.
Springer
• T.M. Lotti et al. Oral Diseases. Springer
• Michael Glick. Burket’s Oral Medicine. PMPH-USA
• Robert P. Langlais et al. Color Atlas Of Common
Oral Diseases.
• Michael. A. Kahn et al. The ADA Practical Guide to
Soft Tissue Oral Diseases. Wiley Blackwell
• G. Laskaris. Pocket Atlas of Oral Disease. Thieme