Scaffolds for large cartilage defects

1. Identify scaffold design parameters.

2. Integrate the designed scaffold in human knee joint model.

3. Check for localization of stresses in the scaffold due to physiological loading.

Effective
Contact
elastic
pressures
modulus

Include models of regeneration in existing models.

6/23/20 EuroMech 604, Oxford 1

 Optimization of loading protocols for Bioreactors

Stable articular
cartilage

+
© LifeTec Group

Mechanical Loading ?
Osteochondral
Grafts

6/23/20 EuroMech 604, Oxford 2

 Multiscale Modelling of Knee Joint

6/23/20 EuroMech 604, Oxford 3