Professional Documents
Culture Documents
Radiotherapy and
Anesthesia
TYPES
1. Unipolar cautery.
2. Bipolar cautery. It is safer because its effect is seen only in between electrode
points. Adjacent tissues will never get damaged.
2. Cutting cautery: Here temperature is 1000°C which disintegrate the tissues. It is not
hemostatic.
Disadvantages
• Infection.
• Cauterization of normal tissues.
• Explosive problems.
• Diathermy burn to the patient where diathermy plate is kept.
• Burn injury or electrical shock to surgeon and assisting personnel.
Precautions
• Proper earthing.
• Avoid loose contact of electrodes.
• It should be kept off when not in use during procedure.
A diathermy machine showing cutting, coagulation and bipolar energy sources.
Cutting and coagulation modes are plugged in.
Monopolar cautery (Blend) used for raising skin flaps during
thyroidectomy
LASERS IN SURGERY
(Light Amplification Stimulated Emission of Radiation).
Molecules are placed in a compact area and power is passed through this so as to
activate the molecules . Molecules get activated at different periods and move in
different directions, which they hit to each other releasing energy. This energy is
allowed to act through optical system to the area wherever required.
Argon Laser.
Yttrium-Aluminium Garnet Laser (YAG Laser).
C02 Laser.
Neon Laser.
Holmium Laser.
Erbium Laser.
Uses of Laser
In cranial surgery in children.
All reflecting instruments should be avoided otherwise laser will reflect and can
Injure normal tissues or the working team in the OT itself.
Disadvantage
• Aims of radiotherapy:
a. In early cancer, eradication of tumor with preservation of structure and function of
normal tissue.
b. In advanced cancer, palliation of symptoms from either the primary tumor or
metastases to improve the quality of life.
i. Teletherapy
The beams of radiation are generated at a distance and aimed at the tumor within the
patient. It is also known as external beam radiotherapy and is most commonly used
form of radiotherapy.
Its advantages are:
• It can deliver high doses of radiotherapy to deep seated tumors.
• There is more homogenous distribution of radiation energy.
• It is skin sparing and avoids skin reactions.
• There is reduced absorption in the bones.
• There is reduced lateral scattering into adjoining Tissues
ii. Brachytherapy
The radioactive source is implanted directly into or adjacent to tumor tissue. It usually
requires an operative procedure and delivers concentrated radiation doses into the
tumor tissue. The doses are relatively high in comparison to doses received by the
surrounding normal tissue.
If radiation source is introduced into tissues it is called interstitial radiotherapy. If
radiation source is introduced into body cavities, it is called intracavitatory
radiotherapy. Various radioactive isotopes used are cobalt 60, iridium 192, caesium
137 and iodine 125.
Its advantages are:
• Sources are introduced and removed under remote control thus preventing exposure
to medical personnel.
• Position of applicator can be checked under X-rays.
• Precise dose of radiation can be delivered to the tumor tissue.
Hence, its unit is called as Rad (Radiation absorbed dose). A Rad is 100 ergs of energy
deposited per gram of tissue.
A Gray (Gy) is equal to 100 rads.
Clinical Applications of Radiotherapy
Treatment Goals
Based on the type of tumor, stage of disease and condition of the patient,
radiotherapy can be used in four settings:
i. Curative
ii. Palliative
iii. Adjuvant
iv. Prophylactic
i. Curative radiotherapy:
Aim of the treatment is to eliminate all malignant cells. High doses of radiotherapy are
given. It involves high cost and patient inconvenience due to long courses of
treatment. There is considerable toxicity due to normal tissue damage.
Curative radiotherapy has a special role in areas where preservation of anatomy
and functions is of critical importance, e.g. carcinoma tongue or larynx can be
destroyed by radiotherapy or removed by surgery and the chances of survival are the
same. But advantage of retaining speech is worth considering with curative
radiotherapy.
• Hodgkin’s lymphoma
• Head and neck cancers
• Carcinoma breast
• Gynecologic cancers (cervix, ovary, uterus)
• Prostate cancer
• Carcinoma esophagus
• Carcinoma anal canal
• Testicular tumors
• Medulloblastoma
• Lung cancer (non-small cell)
ii. Palliative radiotherapy:
Aim of treatment is to control symptoms to improve the
quality of life. Minimum doses of radiotherapy are given to achieve maximum control
and minimum side effects. Short courses of treatment are given to avoid patient
inconvenience and to limit the cost.
Organs having rapid proliferation of cells are most sensitive to radiotherapy, e.g. bone
marrow, ovaries, testes, vascular endothelium and mucosal lining of intestinal tract.
Organs with less renewal of cells are more resistant to radiotherapy, e.g. heart, skeletal
muscles, bones and nerves.
Acute toxicity includes skin erythema and ulceration, mucositis and bone marrow
depression. Most of these can be alleviated by interruption of treatment. Chronic
toxicities are more serious.
The most serious late toxicity is development of second solid tumor in or near site of
radiations, e.g. development of carcinoma breast in females after chest irradiation.
Toxicity of radiotherapy