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Andi Mahavira
Triad kardiovaskular :
• Irama jantung (Rate)
• Volume
• Miokardium (pompa)
Cardiac
Cardiac Output
Output Total
Total Peripheral
Peripheral Resistance
Resistance
Stroke
Stroke Volume
Volume Heart
Heart Rate
Rate
Preload
Preload Contractility Afterload
Cardiogenic Shock: Definition
• Systolic blood pressure <90 mmHg for >30 minutes or
vasopressors required to achieve ≥ 90 mmHg
• Pulmonary congestion or pulmonary capillary wedge pressure (PCWP) >18 mmHg
• Signs of impaired organ perfusion (at least 1)
– Altered mental status
– Cold, clammy skin and extremities
– Oliguria with urine output <30 mL/hour
– Serum lactate >2.0 mmol/L
• Reduced Cardiac index (< 1.8 L/min/m2 without support, and 2.0-2.2 L/min/m2
with support) (optional)
Thiele H and Zeymer Uwe. The ESC Textbook of Intensive and Acute Cardiovascular Care,2015: 441 – 448
European Heart Journal (2008) 29, 2388–2442
European Heart Journal (2012) 33, 1787–1847
ACS TREAT UNDERLYING CAUSE:
CATH PCI
CABG
European Heart Journal (2012) 33, 1787–1847
Ponikowski et al. Eur Heart J 2016; 37(27): 2129-2200
Management of patients with acute heart
failure based on clinical profile
during an early phase
► Laki-laki, 54 tahun riwayat PCI 1 tahun yang lalu, datang ke IGD dengan
keluhan sesak nafas yang makin berat sejak 1 hari yang lalu. 2 hari
sebelumnya pasien sering mengeluh nyeri dada.
► PF : pasien tampak gelisah,
► TD 70/40 mmHg HR 108 x/mnt
► RR 30 x/mnt , Ronki basah ½ lapang paru
► Saturasi 88% (room air)
► JVP meningkat
► Nadi lemah dan Akral dingin
• Apa masalah pada pasien ini ?
• Profil Hemodinamik ?
Diuretik
Dry WET Vasodilator
Warm
A B
L C
• Syok Kardiogenik
• STEMI akut Killip 4
Inotropic drugs :
Cold Dobutamine
Milrinone
Levosimendan
IABP
Management of patients with acute heart
failure based on clinical profile during an
early phase
• Scirica BM and Morrow DA. Braunwald’s Heart Disease, 10th ed, 2015: 1068 –
1094
• Kardioversi
A. Free wall Rupture
B. Ventricular septal rupture
C. Papillary muscle rupture
• Echocardiography
• IABP (Bridging)
• Surgical /
Percutaneous
Intervention
Other Acute
Mechanical Cause
• chest trauma or cardiac intervention, or
• acute native or prosthetic valve incompetence
secondary to
• endocarditis,
• aortic dissection
• thrombosis and
• Cardiac tumours
• Echocardiography
• Surgical / percutaneous intervention
Basic Principle of IABP
•• inWhen the
selected balloon
patients is suddenly
with deflated,
acute myocardial the pressure
ischaemia within the aorta
or infarction
drops
before, during and
quickly AFTERLOAD
after REDUCTION
percutaneous or surgical revascularization.
Ponikowski et al. Eur Heart J 2016; 37(27): 2129-2200
Shock /
Hypotension
• Thrombolysis,
S1 Q3 T3 • Catheter-based or
• Goldhaber SZ. Braunwald’s Heart Disease, 9th ed, 2012: 1679 – 1695 Surgical Embolectomy.
• Ponikowski et al. Eur Heart J 2016; 37(27): 2129-2200
Circulation. 2000;102(suppl 1):I-172–I-216 (26).
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