Professional Documents
Culture Documents
Dr Babak masoumi
Assistant Professor of Emergency Medicine,
Emergency Department, Alzahra General Hospital,
Isfahan University Of Medical Sciences
Methanol
colorless,
volatile,
slightly sweet-tasting alcohol.
It is a product of :
natural fermentation
and
originally was manufactured
from
30 to 60 minutes
after ingestion.
Transdermal
And
respiratory tract absorption
also has resulted in
toxicity,
especially in infants.
Certain occupations, including
painting,
glazing,
varnishing,
lithography, and
printing,
are at high risk for inhalational exposure to
methanol.
Inhalational abuse of methanol is a recent trend that
can result in toxic serum levels.
• In adults,
the smallest lethal dose
reported is
15 mL of 40% methanol;
Optic neuropathy
And
putaminal necrosis
are the
two main complications
of
severe methanol poisoning.
Long-term morbidity:
• takes the form of:
visual impairment,
including:
blindness,
parkinsonian motor dysfunction,
characterized by:
hypokinesis
rigidity.
• The primary sites of ocular injury are the
retrolaminar optic nerve and retina.
• Methanol adversely affects other areas of the CNS,
specifically the basal ganglia.
Bilateral, symmetrical putaminal hypodensities,
hemorrhages, or cystic lesions are characteristic,
occurring in 13.5% of patients.
hypomagnesemia,
hypokalemia,
hypophosphatemia,