The document discusses an abscess of the kidney caused by Klebsiella pneumoniae bacteria that produces extended-spectrum beta-lactamase. Meropenem, a carbapenem antibiotic, is the treatment of choice and should be administered intravenously at 1 gram every 8 hours for 14 to 21 days to effectively treat the infection. A study found that carbapenem therapy was associated with improved survival compared to piperacillin-tazobactam for patients with extended-spectrum beta-lactamase bacteremia.
The document discusses an abscess of the kidney caused by Klebsiella pneumoniae bacteria that produces extended-spectrum beta-lactamase. Meropenem, a carbapenem antibiotic, is the treatment of choice and should be administered intravenously at 1 gram every 8 hours for 14 to 21 days to effectively treat the infection. A study found that carbapenem therapy was associated with improved survival compared to piperacillin-tazobactam for patients with extended-spectrum beta-lactamase bacteremia.
The document discusses an abscess of the kidney caused by Klebsiella pneumoniae bacteria that produces extended-spectrum beta-lactamase. Meropenem, a carbapenem antibiotic, is the treatment of choice and should be administered intravenously at 1 gram every 8 hours for 14 to 21 days to effectively treat the infection. A study found that carbapenem therapy was associated with improved survival compared to piperacillin-tazobactam for patients with extended-spectrum beta-lactamase bacteremia.
Tamma P, Han J, Rock C, Harris A, Lautenbach E, Hsu A et al. Carbapenem Therapy Is Associated With Improved Survival Compared With Piperacillin-Tazobactam for Patients With Extended-Spectrum -Lactamase Bacteremia. Clinical Infectious Diseases. 2015 Am Fam Physician. 2017 Nov 15;96(10):648-654.
Vonoprazan Fumarate, A Novel Potassium-Competitive Acid Blocker, in The Management of Gastroesophageal Reflux Disease: Safety and Clinical Evidence To Date