Drug Study

Drug Name Classification Mechanism of Indication Contraindication Adverse Effects Nursing

Action Responsibilities

Generic Pharmacological: Has analgesic, Relief of signs Contraindicated CNS: dizziness, Instruct patient to take
Name: Cyclooxygenase anti- and symptoms of with allergies to headache, celecoxib exactly as
Celecoxib (COX-2) inflammatory, and osteoarthritis, sulphonamides,  insomnia directed. Do not take
antipyretic rheumatoid celecoxib, more than prescribed
Dosage: Therapeutic: properties. arthritis, NSAIDs, or CV: Stroke, dose. Increasing doses
200 mg 1 Anti- ankylosing aspirin Thrombosis, does not appear to
cap BID PO inflammatory Therapeutic spondylitis, and Edema, increase effectiveness
NSAIDS Effect(s): juvenile Hypertension
Decreased pain rheumatoid Advise patient to notify
and arthritis. GI: GI bleeding, health care
inflammation cau abdominal professional promptly if
sed by arthritis or Management of pain, diarrhea, signs or symptoms of
spondylitis. acute pain. dyspepsia, GI toxicity (abdominal
flatulence, pain, black stools), skin
Decreased pain. nausea rash, unexplained
weight gain, edema
occurs
Drug Name Classification Mechanism of Indication Contraindication Adverse Effects Nursing
Action Responsibilities

Generic Fluid and Calcium is an Antacid, Hypercalcemia, Constipation, Administer as antacid1

Name: electrolytic essential element calcium bone tremors, flatulence, hour after meal and at
Calcium and water for regulating the supplement, severe renal diarrhea, renal bed time.
Carbonate balance excitation osteoporosis failure, dysfunction, acid
agent;  threshold of hypersensitivity rebound. Administer as
Dosage: replacement nerves and supplement 1½ hours
Adult 1-2 solution muscles, for blood after meal and at
capsules clotting bedtime.
daily mechanisms,
cardiac function Increase fluid intake
(rhythm, tonicity,
contractility),
maintenance of
renal function, for
body skeleton and
teeth. 
Drug Name Classification Mechanism of Indication Contraindicatio Adverse Effects Nursing
Action n Responsibilities

Generic Analgesic Chemical Effect: Moderate to Tramadol may Tramadol is generally • Assess BP and RR
Name: Binds to mu-opioid moderately increase central well tolerated, and before and
Tramadol receptors .Inhibits severe pain nervous system side effects are periodically during
reuptake and respiratory usually transient. administration.
Dosage 100 of serotonin and depression Commonly reported Respiratory
mg IV norepinephrine in when side effects include depression has not
the CNS. combined with nausea, constipation, occurred with
alcohol, dizziness, headache, recommended
Therapeutic Effect: anesthetics, drowsiness, and dose.
Decreased Pain narcotics, vomiting
tranquilizers or • Assess bowel
sedative function routinely.
hypnotics Prevention
of constipation
should be instituted
with increased
intake of fluids and
bulk and with
laxatives to
minimize
constipating effects.
Drug Name Classification Mechanism of Indication Contraindicatio Adverse Effects Nursing
Action n Responsibilities

Generic Pharmacological: Increases Dietary Use of sodium GI: Nausea, vomiting, • Seek immediate
Name: Multivitamins protection supplement ascorbate in heartburn, diarrhea  health care for sign
Ascorbic mechanism of patients on and symptoms of
Acid the immune To prevent sodium Hematologic: Acute excessive intake of
system, thus vitamin C restriction. hemolytic anemia Vit C including
Dosage 1 tab support healing deficiency in vomiting, severe
OD patients with Use of calcium CNS: Headache headache, diarrhea
poor ascorbate in and skin flushing.
nutritional patient
status receiving
digitalis.
Drug Name Classification Mechanism of Indication Contraindication Adverse Effects Nursing
Action Responsibilities

Generic Pharmacological: Elevates the Prevention Contraindicated CNS: CNS toxicity, Check the doctor’s
Name: Iron preparation serum iron and treatment with allergy to any acidosis, coma and order
Ferrous concentration, of iron- ingredient; death with
Sulfate and is then deficiency sulphite allergy; overdose.  Assess for allergy to
converted to anemias hemochromatosis, any ingredient, sulfite;
Dosage: Hgb or trapped hemosiderosis, GI: GI upset, hemochromatosis,
 1 tab TID in the Dietary haemolytic anorexia, nausea, hemosiderosis,
reticuloendothel supplement anemias vomiting, haemolytic anemias
ial cells for for iron constipation,
storage and Precaution: diarrhea, dark Assess for skin lesions,
eventual Unlabeled use: stools, temporary color; gums, teeth
conversion to a supplemental Use cautiously staining of teeth (color); bowel sounds
usable form of use during with normal iron (liquid
iron epoetin balance; peptic preparations) Monitor blood studies
therapy to ulcer, regional
ensure proper enteritis, Confirm that client
hematologic ulcerative colitis. does have iron
response to deficiency
epoetin
Administer the right
drug in the right dose
and route at the right
time
Drug Name Classification Mechanism of Indication Contraindication Adverse Effects Nursing
Action Responsibilities

Do not crush, chew or

cut tablets and capsules

Give drug with meals

(avoiding milk, eggs,
coffee, and tea)

Administer liquid
preparations in water or
juice to mask the taste
and prevent staining of
teeth; have patient drink
solution with a straw

Do not take this drug

with antacids nor
tetracyclines unless
prescribed

Warn patient that stool

may be dark or green
Drug Name Classification Mechanism of Indication Contraindication Adverse Effects Nursing
Action Responsibilities

Generic Therapeutic: Cefazolin inhibits Used to treat Contraindicated in CV: phlebitis, Instruct patient to report
Name: Anti-Inefectives cell wall bacterial patients thrombophlebitis adverse reaction
Cefazolin  biosynthesis by infections of hypersensitive to promptly 
Pharmacologic: binding Penicillin the skin drug or other GI: diarrhea,
Dosage:  First generation binding proteins cephalosporins. pseudomembrano Tell patient to report
500 mg cephalosphorins which stops Used to treat us colitis, anorexia, discomfort at IV injection
site. 
peptidoglycan moderately Use cautiously in glossitis,
synthesis. severe patients with a dyspepsia, Notify patient to notify
Penicillin binding bacterial history of colitis, abdominal prescriber if a rash
proteins are infections seizure disorders cramps, anal develops or if signs and
bacterial involving the or renal pruritus, oral symptoms of super
proteins that lung, bone, insufficiency. candidiasis infection, such as
help to catalyze joint, stomach, recurring fever, chills and
the last stages of blood heart Prolonged used GU: genital malaise.
peptidoglycan valve, and result in fungal or pruritus
synthesis, which urinary tract. bacterial candidiasis
is needed to superinfection,
maintain the cell including CDAD (C. Hematologic:
wall difficile-associated neutropenia,
disease) which can leukopenia,
occur more than 2 thrombocytopenia
months after , eosinophilia
treatment ends.
Drug Name Classification Mechanism of Indication Contraindication Adverse Effects Nursing
Action Responsibilities

Clinically Use cautiously in Skin:

effective patients erythematous
against hypersensitive to rashes, pruritus,
infections penicillin because pain, indurations,
caused by of the possibility sterile abscesses,
staphylococci of cross-sensitivity tissue sloughing at
and with other beta injection site
streptococci lactin antibiotics.
species of
Gram positive
bacteria