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  • Furans: Reactions and Synthesis

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    maheen aurangzaib
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    This document discusses the reactions and synthesis of furans. It covers reactions of furans with electrophilic reagents like nitration, sulfonation, halogenation, and acylation. It also discusses ring syntheses of furans from 1,4-dicarbonyl compounds using the Paal-Knorr synthesis or from α-halo-carbonyl and 1,3-dicarbonyl compounds using the Feist-Benary synthesis. Examples of notable furan syntheses include those of tris(furanyl)-18-crown-6, furaneol, and ranitidine-Zantac.

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    Heteroclic Compounds-Lecture-9.pptx

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    This document discusses the reactions and synthesis of furans. It covers reactions of furans with electrophilic reagents like nitration, sulfonation, halogenation, and acylation. It also discusses ring syntheses of furans from 1,4-dicarbonyl compounds using the Paal-Knorr synthesis or from α-halo-carbonyl and 1,3-dicarbonyl compounds using the Feist-Benary synthesis. Examples of notable furan syntheses include those of tris(furanyl)-18-crown-6, furaneol, and ranitidine-Zantac.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    11 views25 pages

    Furans: Reactions and Synthesis

    Uploaded by

    maheen aurangzaib
    This document discusses the reactions and synthesis of furans. It covers reactions of furans with electrophilic reagents like nitration, sulfonation, halogenation, and acylation. It also discusses ring syntheses of furans from 1,4-dicarbonyl compounds using the Paal-Knorr synthesis or from α-halo-carbonyl and 1,3-dicarbonyl compounds using the Feist-Benary synthesis. Examples of notable furan syntheses include those of tris(furanyl)-18-crown-6, furaneol, and ranitidine-Zantac.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 25

    Furans

    REACTIONS AND SYNTHESIS


    Reactions with Electrophilic Reagents-
    Substitution at Carbon- Protonation
    Nitration
    Sulfonation
    Halogenation
    Acylation
    Alkylation and Alkenylation
    Condensation with Imines and Iminium Ions
    Mercuration
    Reactions with Oxidizing Agents
    Reactions with Nucleophilic Reagents
    Reactions with Reducing Agents
    Furyl - C – X Compounds; Side -
    Chain Properties
    Oxy - Furans
    Amino - Furans
    Synthesis of Furans
    Ring Syntheses
    From 1,4 - Dicarbonyl Compounds
    The Paal – Knorr Synthesis
    From α - Halo – Carbonyl and
    1,3 - Dicarbonyl Compounds
    The Feist – Benary Synthesis
    From C4O Compounds
    Examples of Notable Syntheses of
    Furans
    Tris(furanyl) - 18 - Crown - 6
    Furaneol
    Ranitidine-Zantac

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