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    The Mannich reaction converts a primary or secondary amine and two carbonyl compounds (one non-enolizable and one enolizable) to a β-amino carbonyl compound using an acid or base catalyst. The reaction was discovered by German chemist Carl Mannich and produces what is known as a Mannich base.

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    The Mannich reaction converts a primary or secondary amine and two carbonyl compounds (one non-enolizable and one enolizable) to a β-amino carbonyl compound using an acid or base catalyst. The reaction was discovered by German chemist Carl Mannich and produces what is known as a Mannich base.

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    23 views4 pages

    Reaction Mechanisms-23-2

    Uploaded by

    maheen aurangzaib
    The Mannich reaction converts a primary or secondary amine and two carbonyl compounds (one non-enolizable and one enolizable) to a β-amino carbonyl compound using an acid or base catalyst. The reaction was discovered by German chemist Carl Mannich and produces what is known as a Mannich base.

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    10- Mannich Reaction

    The Mannich reaction is an organic reaction used to convert a primary


    or secondary amine and two carbonyl compound (one non-enolizable
    and one enolizable) to a β-amino carbonyl compound, also known as a
    Mannich base, using an acid or base catalyst.
    Named after German chemist Carl Mannich.

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