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Clinical Assessment of Gonadal Disorders

The document discusses the clinical assessment of gonads and hypogonadism. It examines ovaries and testes, looking at concordance between biological age and sexual maturation, features of abnormal sexualization, history of pubertal onset and fertility, and previous hormonal therapy or menopause age. Hypogonadism is classified as hypogonadotropic with low estradiol/testosterone and low FSH/LH, or hypergonadotropic with low estradiol/testosterone but elevated FSH/LH. Several conditions affecting the gonads like Turner's syndrome, polycystic ovary syndrome, Sheehan's syndrome, and Klinefelter's syndrome are also examined.

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Leonard Acsinte
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66 views38 pages

Clinical Assessment of Gonadal Disorders

The document discusses the clinical assessment of gonads and hypogonadism. It examines ovaries and testes, looking at concordance between biological age and sexual maturation, features of abnormal sexualization, history of pubertal onset and fertility, and previous hormonal therapy or menopause age. Hypogonadism is classified as hypogonadotropic with low estradiol/testosterone and low FSH/LH, or hypergonadotropic with low estradiol/testosterone but elevated FSH/LH. Several conditions affecting the gonads like Turner's syndrome, polycystic ovary syndrome, Sheehan's syndrome, and Klinefelter's syndrome are also examined.

Uploaded by

Leonard Acsinte
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd

GONADS

Ovaries
Testes
Clinical endocrinological assessment of
gonads

• Concordance between biological age and sexual maturation;


• Presence of abnormal sexualization features according to age
and gender
• History of pubertal onset
• History of fertility
• Previous hormonal therapy
• Menopause age
Hypogonadism

Estradiol FSH/LH
/testosterone
Hypogonadotropic Low Low

Hypergonadotropic Low  Elevated

The initial event marked with red


Ovary
Anatomy
Menstrual cycle - hormones
Menstrual cycle – uterine changes
Turner's syndrome
Turner's syndrome – dorsal feet oedema at
birth
Turner's syndrome –
Pterygium colli (webbed neck)
Turner's syndrome - Pterygium colli
Turner's syndrome –
low hair insertion (M-shape)
Turner's syndrome
Turner's syndrome - webbed neck
Turner's syndrome
Turner's syndrome – cubitus valgus
Turner's syndrome
Turner's syndrome – shield-shaped thorax
Polycystic ovary
Polycystic ovary syndrome
Polycystic ovary
Polycystic ovary
Polycystic ovary
Polycystic ovary
Sheehan’s syndrome
Sheehan’s syndrome - MRI aspect
Sheehan’s syndrome
Sheehan’s syndrome
Klinefelter’s syndrome
Klinefelter’s syndrome
Gynecomastia (before/after surgical correction)
Klinefelter’s syndrome

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