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Significance was set at P<0.05 for all models. All analyses were performed
using SAS version 9.2 (SAS Institute)
Analytical Sample
Results
Discussion
In this large cross-sectional study of nondemented
elderly individuals in the general population, we found:
•a significant association between AF and lower total
brain and gray and white matter volumes
•For both total brain and gray matter volume, the
association was stronger with persistent/permanent
compared with paroxysmal AF
•Participants with AF scored significantly lower on
tests of MEM
AF and Brain volume