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org
GCF (Gynecologic Cancer Foundation) Presentation
www.maketheconnection.org
www.cancer.org
1/Wright/p.21
20/abstract
conclusions

2/Bonnez/p.
576/Figure
12; p. 578/col
1/¶2

3/CCS/p 6/¶2

4/Sellors/Ch.
7/p.9/Figure
7.23.

1. Wright TC Jr, Cox JT, Massad LS, et al, for the ASCCP-Sponsored
Consensus Congress. JAMA. 2002;287:2120–2129. 2. Bonnez W. In:
Richman DD, Whitley RJ, Hayden FJ, eds. Washington, DC: American
Society for Microbiology Press; 2002:557–596. 3. Canadian Cancer
Society. Cervical Cancer: What you need to know. Available at:
1/Sellors/Ch http://www.cancer.ca/vgn/images/portal/cit_86751114/63/40/151140772cw
. 4/p. 1/¶ 1; _library_wyntk_cervical_en.pdf. Accessed March 13, 2006. 4. Reprinted
p.5/¶ 2 with permission from Sellors JW, Sankaranarayanan R, eds. Colposcopy
and Treatment of Cervical Intraepithelial Neoplasia. A Beginner’s Manual.
1/Sellors/Ch
. 7/p. 1/¶ 1; Lyon, France: International Agency for Research on Cancer; 2003.
p. 6/¶ 3,
Figure 7.12.

1/Sellors/Ch.
www.maketheconnection.org
www.cdc.gov/std/HPV/STDFcat-HPV.htm
1/Parham/p.
S14/Table 1.
2/Schink/p. 5/
col 2/¶2.
3/Uyar/p. 227/
abstract.
4/Kulasingam/p.
1754/Table 3.

2/Schink/p.
5/col 2/¶1.
5/Selvaggi/
p. 1506/col
1/¶1, 3.
6/Chacho/p.
137/col 2/¶5

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3. Sung HY, Kearney KA, Miller M, Kinney W, Sawaya GF, Hiatt RA. Papanicolaou smear history
and diagnosis of invasive cervical carcinoma among members of a large prepaid health plan.
2/Crum/p. Cancer. 2000;88:2283–2289.
368/col 1/¶2; 4. Schink JC. Strategies for detecting cervical dysplasia: Visual inspection, spectroscopy, and
col 2/¶1 speculoscopy. OBG Manag. 2003;(suppl):5–8.
5. Selvaggi SM. Implications of low diagnostic reproducibility of cervical cytologic and histologic
diagnoses. JAMA. 2001;285:1506–1508.
3/Sung/p. 6. Chacho MS, Mattie ME, Schwartz PE. Cytohistologic correlation rates between conventional
2285/col Papanicolaou smears and ThinPrep cervical cytology: A comparison. Cancer. 2003;99:135–140.
2/¶3, 4 7. Saslow D, Runowicz CD, Solomon D, et al. American Cancer Society Guideline for the early
detection of cervical neoplasia and cancer. CA Cancer J Clin. 2002;52:342–362.
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5/ col 2/¶1. 9. Kulasingam SL, Hughes JP, Kiviat NB, et al. Evaluation of human papillomavirus testing in
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5/Selvaggi/
p. 1506/col
American Cancer Detailed Guide. American Cancer Society Online
Publication. http://www.cancer.org
The picture on your left is the magnified image of a
normal cervix after the application of Acetic acid.

The picture to your right is the magnified image of a


cervix with an abnormal Aceto white lesion- ie a
Positive tests.
1/Sellors/Ch
. 8/p. 4/ Photos
Figures 3.5 courtesy of
and 8.8 Dr. J.
Monsonego.

1. Reprinted with permission from Sellors JW, Sankaranarayanan R,


eds. Colposcopy and Treatment of Cervical Intraepithelial Neoplasia. A
Beginner’s Manual. Lyon, France: International Agency for Research on
Cancer; 2003.
1/Sellors/Ch
. 8/p. 2/¶
5,6.
Stage I is carcinoma strictly confined to the cervix; extension to the uterine corpus should be
disregarded.
Stage IA: Invasive cancer identified only microscopically. All gross lesions even with superficial invasion
are stage Ib cancers. Invasion is limited to measured stromal invasion with a maximum depth of 5 mm*
and no wider than 7 mm. [Note: *The depth of invasion should not be more than 5 mm taken from the
base of the epithelium, either surface or glandular, from which it originates. Vascular space involvement,
either venous or lymphatic, should not alter the staging.]
Stage IA1: Measured invasion of the stroma no greater than 3 mm in depth and no
wider than 7 mm diameter.
Stage IA2: Measured invasion of stroma greater than 3 mm but no greater than 5 mm
in depth and no wider than 7 mm in diameter.
Stage IB: Clinical lesions confined to the cervix or preclinical lesions greater than stage IA.
Stage IB1: Clinical lesions no greater than 4 cm in size.
Stage IB2: Clinical lesions greater than 4 cm in size.
Stage II is carcinoma that extends beyond the cervix but has not extended onto the pelvic wall. The
carcinoma involves the vagina, but not as far as the lower third.
Stage IIA: No obvious parametrial involvement. Involvement of up to the upper two thirds of the vagina.
Stage IIB: Obvious parametrial involvement, but not onto the pelvic sidewall.

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