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  • Diagnosis: HCC Dapat Didiagnosa Dengan Cara: - Presentasi Klinis - Investigation - Staging

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    nabil abdurrahman
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    This document discusses the diagnosis of hepatocellular carcinoma (HCC) through clinical presentation, investigations including imaging tests, tumor markers, viral markers, and liver biopsy. It describes the stages of HCC seen on MRI and the Okuda and Child-Turcotte-Pugh staging systems. Screening for HCC is recommended every 6 months for at-risk patients using AFP levels and ultrasound to detect HCC at treatable, asymptomatic stages.

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    Hepatocelullar Carcinoma

    Original Title

    Diagnosis HCC

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    This document discusses the diagnosis of hepatocellular carcinoma (HCC) through clinical presentation, investigations including imaging tests, tumor markers, viral markers, and liver biopsy. It describes the stages of HCC seen on MRI and the Okuda and Child-Turcotte-Pugh staging systems. Screening for HCC is recommended every 6 months for at-risk patients using AFP levels and ultrasound to detect HCC at treatable, asymptomatic stages.

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    5 views10 pages

    Diagnosis: HCC Dapat Didiagnosa Dengan Cara: - Presentasi Klinis - Investigation - Staging

    Uploaded by

    nabil abdurrahman
    This document discusses the diagnosis of hepatocellular carcinoma (HCC) through clinical presentation, investigations including imaging tests, tumor markers, viral markers, and liver biopsy. It describes the stages of HCC seen on MRI and the Okuda and Child-Turcotte-Pugh staging systems. Screening for HCC is recommended every 6 months for at-risk patients using AFP levels and ultrasound to detect HCC at treatable, asymptomatic stages.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 10

    Diagnosis

    HCC dapat didiagnosa dengan cara :


    • Presentasi klinis
    • Investigation
    • Staging
    1. Investigation
    • Imaging : • Tumor marker
    - AFP measurement
    - Ultrasonography
    - Viral marker
    - CT Scan • Liver radio isotope scans
    - MRI • Liver function test
    • Liver Biopsy : - Serum bilirubin
    - AST
    - percutaneous aspiration or core
    - ALT
    biopsy
    - ALP
    - Prothrombin time
    - Serum albumin
    Alur penegakan diagnosa
    Studi MRI menunjukkan gambaran
    HCC pada beberapa stage
    A. Very early stage, (1 lesi 1.7cm),
    B. Early stage (2 lesi 2.4 dan 1.2cm)
    C. Intermediate stage (lesi multiple)
    D. Advanced (massa yang besar dan
    asites)
    2. Staging : OKUDA staging system

    • Stage 1 : 0 point
    • Stage 2 : 1-2 points
    • Stage 3 : 3-4 points
    Skoring CHILD-TURCOTTE-PUGH

    • Stage A : 5-6 points


    • Stage B : 7-9 points
    • Stage C : 10-15 points
    Interpretasi
    Skrining HCC
    • Target : dapat disembuhkan tanpa gejala
    • Metode : AFP (setiap 6 bulan) & Ultrasound
    • Indikasi : untuk pasien yang memiliki resiko HCC
    - Sirosis
    - Hepatitis B,C
    - Konsumsi alcohol
    - Genetic hemochromatosis
    - Hepatitis autoimun
    - Hepatitis bilier primer
    - Defisiensi alpha1 antitrypsin

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