Fracture

Healing
Fauziarti Azimah - 1940312128

Preceptor:
dr. Rizki Rahmadian, Sp. OT(K), M. Kes
 Fracture healing

youtube: Amgen
 Definition
Fracture healing involves a complex and sequential set of
events to restore injured bone to pre-fracture condition

Ayer A. 2020. Fracture Healing. https://www.orthobullets.com/basic-science/9009/fracture-healing. Accessed October 2020

Ayer A. 2020. Fracture Healing. https://www.orthobullets.com/basic-science/9009/fracture-healing. Accessed October 2020
 Hematoma
 Days 1-5
 Hematoma (fibrin clot)
 Macrophages
 Inflammatory leukocytes
 Osteoprogenitor cells
 Hematopoietic cells secrete
growth factors

Green WB. 2005. Netter's Orthopedics1e

Sheen JR, Garla VV. Fracture Healing Overview. In StatPearls [Internet]. 2020. Accessed October 2020 https://www.ncbi.nlm.nih.gov/books/NBK551678/
 soft Callus formation
 Days 5-11
 Inflammation triggers cell
division and growth of new blood
vessels
 Angiogenesis
 Chondrocytes secrete collagen
and proteoglycans
 Creates fibrocartilage
Green WB. 2005. Netter's Orthopedics1e
Sheen JR, Garla VV. Fracture Healing Overview. In StatPearls [Internet]. 2020. Accessed October 2020 https://www.ncbi.nlm.nih.gov/books/NBK551678/
 hard Callus formation
 Days 11-28
 Enchondral ossification
 Bone formation
 Soft callus turns to hard
callus (woven bone)

Green WB. 2005. Netter's Orthopedics1e

Sheen JR, Garla VV. Fracture Healing Overview. In StatPearls [Internet]. 2020. Accessed October 2020 https://www.ncbi.nlm.nih.gov/books/NBK551678/
 bone remodelling
 Day 18 onwards, lasting months-
years
 Osteoclastic and osteoblastic activity
converts woven bone to lamellar
bone with true haversian systems.
 Normal bone contours are restored;
even angulation may be partially or
completely corrected

Green WB. 2005. Netter's Orthopedics1e

Sheen JR, Garla VV. Fracture Healing Overview. In StatPearls [Internet]. 2020. Accessed October 2020 https://www.ncbi.nlm.nih.gov/books/NBK551678/
 Multiple factors affect fracture healing

 Local factors
 Sistemic factors

Sheen JR, Garla VV. Fracture Healing Overview. In StatPearls [Internet]. 2020. Accessed October 2020 https://www.ncbi.nlm.nih.gov/books/NBK551678/
 Multiple factors affect fracture healing

 Local factors
 Fracture characteristics
 Infection
 Blood supply

Sheen JR, Garla VV. Fracture Healing Overview. In StatPearls [Internet]. 2020. Accessed October 2020 https://www.ncbi.nlm.nih.gov/books/NBK551678/
 Multiple factors affect fracture healing

 Sistemic factors
 Advanced age
 Obesity
 Anemia
 Endocrine conditions - Diabetes mellitus, Parathyroid disease, and
Menopause
 Steroid administration
 Malnutrition
 Smoking
Sheen JR, Garla VV. Fracture Healing Overview. In StatPearls [Internet]. 2020. Accessed October 2020 https://www.ncbi.nlm.nih.gov/books/NBK551678/
 promote/stimulate fracture healing

 Dietary supplements
 Bone stimulators
 Bone graft

Sheen JR, Garla VV. Fracture Healing Overview. In StatPearls [Internet]. 2020. Accessed October 2020 https://www.ncbi.nlm.nih.gov/books/NBK551678/
It is much more important to know what sort of a
patient has a disease than what sort of a disease a
patient has.

—William Osler
Thanks
Do you have any questions?

CREDITS: This presentation template was created by Slidesgo, including

icons by Flaticon, and infographics & images by Freepik