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the
The timeframe
Drug of Target in which
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EPIDEMIOLOGY
One in every 200 patients presents at the ED with a suspected hypertensive emergency with
heart failure, stroke, and myocardial infarction represented the largest proportion of all
hypertensive emergencies, followed by intracranial haemorrhage and aortic dissection,
whereas the incidence of hypertensive emergencies with advanced retinopathy was quite low.
PATHOPHYSIOLOGY
Thrombotic
Renal
Encephalopathy Mycroangiop
athy
• In patients presenting at the ED with malignant hypertension, secondary causes can be found in 20–40% and most often consist
of renal parenchymal disease and renal artery stenosis, whereas endocrine.
• Marked activation of the renin–angiotensin system is often present and associated with the degree of microvascular damage.
PATHOPHYSIOLOGY
Thrombotic
Renal
Encephalopathy Mycroangiop
athy