Bacterial Blood Stream

Infection in Southern
Ethiopia
Mengistu Hailemariam1*, Tsegaye Alemayehu1, Asnakech Agegnehu2, Mulubrhan Ali1, Enkosilassie Mitiku2 and Elshaday
Azerefegne2

1Department of Medicine, Hawassa University College of Medicine and Health Sciences, Sidamo, Ethiopia
2Department of Medicine, Hawassa University Comprehensive and Specialized Hospital, Awassa, Ethiopia

PRESENTED BY:
MAYBELYN DELA CRUZ
ABIGAIL ARCIBAL
ROBIN MARQUEZ
 ABSTRACT
Children’s blood stream infections mainly due to resistant pathogens
found to be a higher risk of hospital mortality in low and middle
income countries. This study intended to assess the bacterial profile
and drug resistance of isolates of blood stream infection among under-
5 children in Southern Ethiopia.
INTRODUCTION
BLOOD STREAM INFECTION
 Blood Stream Infection (BSI) is the most
common causes of morbidity and mortality in
children across the world

  The burden of sepsis is most likely highest in

low- and middle-income countries.
 INTRODUCTION
 Blood stream infection (BSI) can be
preventable with timely attention, coherent
antimicrobial therapy and supportive care,
so far higher death rates reported in
developing countries

AIM OF THE STUDY:

to determined the extent of bacteria cause of
blood stream infection
It is estimated
about 3 million
newborn and
1.2 million
children suffer
from sepsis
globally every
year.
 TIME AND
PLACE
The study was carried out in
Southern Ethiopia to record the
prevalence of blood stream
infection in children from
January 2019 to December 2020.
 MATERIALS
AND METHOD
 COLLECTION OF BLOOD SAMPLES

Incubated at
35°C-37°C
B

1-2 mL of blood was Added to trypic soya

collected aseptically broth in a ratio of
blood to broth
ANALYSIS
 The data was entered and analysed using
SPSS version 20 (IBM Corporation, Armonk,
NY, USA). Descriptive statistics like
frequency and percentages of categorical
variables was calculated. Bivariate
comparisons using Chi-square logistic
regression were employed to assess the
association between variables. A p-value of
less than 0.05 was considered as statistical
significance
 RESULTS
GENDER

 We processed a total of 323 blood cultures from

child who were suspected for blood stream
infection during the study period.

 The ratio of male were 172 (53.3%) and 151

(46.7%) females.

MALE FEMALE
 RESULTS
PROCESSED CLINICAL
 From all processed clinical samples, SAMPLES
116/323 (35.9%) were culture positive for
invasive bacterial infection.
 Among recorded 116 bacterial infections,
62 (53.4%) were male and 54 (46.6%)
female.
 Dominant number of patients, 142 (44%) as
well the highest positivity rate, 52.6% was
recorded among the age group of 0-28 day
neonates, p=0.003 POSITIVE NEGATIVE
RESULTS
Children who were suspected for blood stream infection during the study
period.

151 Total : 323

172

MALE FEMALE
RESULTS
Culture positive for positive bacterial infection
FREQUENCY PERCENTAGE

Male 62 53%

Female 54 64%

Total 116 100%

RESULTS

CHILD WHO 323

WERE 35.9% were
SUSPECTED culture positive
FOR BIS for invasive
bacterial
RECORDED 116 infection.
BACTERIAL
INFECTION
ABSTRACT INTRODUCTION

METHODS ANALYSIS

RESULTS CONCLUSION
BACKGROUND

01 02 03

Despite being red, Mercury is the Saturn is composed of

Mars is actually a cold smallest planet of hydrogen and helium
place them all

04 05 06

Venus is the second Neptune is the farthest Jupiter is the biggest

planet from the Sun planet from the Sun planet of them all
GOALS
Mars
Despite being red, Mars is actually a
cold place full of iron oxide dust

Venus
Venus has a beautiful name and is the
second planet from the Sun

Mercury
Mercury is the closest planet to the Sun
and the smallest one
RESEARCH AND PUBLICATIONS

“Venus might have a beautiful “Neptune is the farthest planet from

name, but its atmosphere is the Sun and the fourth-largest in
extremely poisonous” the Solar System”

by VENUS by NEPTUNE

“Mercury is the closest planet to “Jupiter is the biggest planet in the

the Sun and the smallest one in the Solar System and the fourth-
Solar System” brightest object in the sky”

by MERCURY by JUPITER
LIST OF REFERENCES

● Here you can list your reference websites or publications

● Here you can list your reference websites or publications
● Here you can list your reference websites or publications
● Here you can list your reference websites or publications
● Here you can list your reference websites or publications
● Here you can list your reference websites or publications
FACTORS TO CONSIDER

Mars Mercury
Despite being red, Mars is actually Mercury is the closest planet to the
a cold place full of iron oxide dust Sun and the smallest one
CLINICAL TRIAL

PRECLINICAL PHASE 1 PHASE 2 PHASE 3

Efficacy &
Lab Studies Human Safety Expanded Safety
Safety

3,000 4,520 12,523

Mercury is the
closest planet to
the Sun
CLINICAL TIMELINE

Venus is the second Saturn is composed

planet from the Sun of hydrogen and
helium
STEP 02 STEP 04

STEP 01 STEP 03
Despite being red, Earth is the planet
Mars is a cold place where we live on
 CONCLUSION
A high level of blood stream infection
accompanied by high drug resistant isolates was
reported. The great burden in neonate than other
children was reported. As a result to reduce the
burden the hospital administrators need to
facilities effective infection prevention and
control programmes, effective hygiene practices
and well-functioning environment along with
educating patient about proper hygiene
practices.
OUR TEAM

Dr. John Doe Dr. Jenna Patterson

Mercury is the closest planet to the Mercury is the smallest planet in
Sun and also the smallest one in the our Solar System—in fact, it’s only
Solar System a bit larger than the Moon
CONCLUSION

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