This document discusses properties of cardiac muscle and the cardiac action potential. It notes that cardiac muscle action potential has a plateau phase during which the heart cannot be restimulated, preventing cardiac muscle tetanus. The action potential results in contraction and relaxation of the heart. Phases of the cardiac action potential and refractory period are described. Conductivity, recruitment, energy source, blood flow, oxygen extraction, rhythmicity, and automaticity of cardiac muscle are compared to skeletal muscle. The conductive system of the heart including the sinoatrial node, atrioventricular node, bundle of His, and Purkinje fibers is outlined.
This document discusses properties of cardiac muscle and the cardiac action potential. It notes that cardiac muscle action potential has a plateau phase during which the heart cannot be restimulated, preventing cardiac muscle tetanus. The action potential results in contraction and relaxation of the heart. Phases of the cardiac action potential and refractory period are described. Conductivity, recruitment, energy source, blood flow, oxygen extraction, rhythmicity, and automaticity of cardiac muscle are compared to skeletal muscle. The conductive system of the heart including the sinoatrial node, atrioventricular node, bundle of His, and Purkinje fibers is outlined.
This document discusses properties of cardiac muscle and the cardiac action potential. It notes that cardiac muscle action potential has a plateau phase during which the heart cannot be restimulated, preventing cardiac muscle tetanus. The action potential results in contraction and relaxation of the heart. Phases of the cardiac action potential and refractory period are described. Conductivity, recruitment, energy source, blood flow, oxygen extraction, rhythmicity, and automaticity of cardiac muscle are compared to skeletal muscle. The conductive system of the heart including the sinoatrial node, atrioventricular node, bundle of His, and Purkinje fibers is outlined.
Abu Ahmed 2019 7. Action potential of cardiac muscle
Cardiac muscle action potential
has a plateau phase. During the plateau phase the heart cannot be restimulated. the plateau phase prevent the tetanus of cardiac muscle. The action potential results in a mechanical response: contraction (systole) followed by relaxation (diastole). Ionic Basis Of Ventricular Action Potential Phase 0: rapid depolarization: due to Na+ influx through fast Na+ channels. Phase 1: initial repolarization: due to K+ efflux through transient K+ channels. Phase 2: plateau: due to Ca++ influx through slow Ca++ channels.( A balance is created between influx of Ca+ and efflux of K+). Phase 3: Late rapid repolarization, due to K+ efflux . Phase 4: Resting membrane potential . 8. Refractory period (RP):-
Itis very long compared with
that in nerve or skeletal muscle. Prolong due to presence of plateau phase Includes absolute RP and relative RP. Cardiac muscle Skeletal muscle 9. Conductivity The ability of the cardiac muscle to conduct the impulses that initiated in the SA node. This takes place by conductive system. 10. Recruitment:- No recruitment in cardiac muscle because heart function as one unit. 11. Source of energy
Fat is main source of energy.
Under basal condition 60% of cardiac needs are provided by free fatty acids,35% by carbohydrates and 5% by amino acids and ketones. 12. Blood flow Blood flow to the heart mainly during diastole. The left ventricle receives blood only during diastole and the right ventricle receives blood during both systole and diastole . 13. Oxygen extraction:- Cardiac muscle extracts higher amount of oxygen (75%)than skeletal muscles(25%). 14.Rhythmicity :- Heart contracts regularly. This also due to presence of conductive system. 15.Automaticity:-
Cardiac muscle produce action
potential spontaneously. Due to presence of pacemaker (S.Anode). Skeletal muscle can not contract in the absence of external stimulation. Conductive system It consist of:- Sinoatial node(SAnode). Internodal atrial pathways. Atrioventricular node(AVnode). Bundle of His & its branches. Purkinje fibers. Conductive system Therate of discharge of SA node is faster than other conductive system, therefore its determine the heart rate and called the pace maker of the heart. Rate of discharge of SA node without innervation 100beat/min. With innervation about 70beat/min this is due to parasympathetic which dominates. The AV node, is the only conducting pathway between the atria &ventricles. The AV node found in the right atrium on the right side of interatrial septum above the fibrous ring. The AV node delay Impulses conduction from atria to ventricles to complete ventricular filling. AV node discharge rate about 45beat/min. AVnode become the cardiac pace maker if the SA node is diseased (e.g sinus syndrome).