Breathlessness Increased since 3 days ago. , was not affected by activity, weather and food. Fatique since 1 week ago Decrease of appetite since 1 week ago Heartburn increased since 1 week ago, was affected by food, was not affected by activity and rest. spread (-) Nausea since 1 week ago, vomit (-) Fever since 3 days ago continuously ,sweating (-) shivering (-) Cough since 3 days ago with white phlegm (+) bloody(-) History of bleeding: Gum bleeding (-) Skin bleeding/ bluish on the skin (-), nosebleed(-) black defecation before( -) black vomit before (-) Defecation and Micturition was was normal The patient is known to have CKD and has received Hemodialysis since 2 years ago. • History of HT (-) • History of DM (-) Physical Examination • Consciousness level: CMC