Central IV Production & Admixture

Services (CIPAS): the state of the art

Mahdi A.
March 2019
 Introduction
• In hospitals, the major part of the drugs is
administered by intravenous way and the
majority of the reconstitution of injectable
drugs are carried out right before the
administration to the patient by the nursing
staff.
• The risks and errors related to the preparation
and the administration of the injectable drugs
are numerous.
 Intro…
• Compounding involves the preparation,
mixing, assembling, packaging, and labeling of
a drug or device in accordance with a licensed
practitioner's prescription. This may include
the reconstitution or manipulation of
commercial products.
• In addition to the preparation of the mixtures
of parenteral nutrition as well as doses of
anticancer chemotherapy
 Intro…
• The reconstitution of the intravenous treatments
by a centralized intravenous admixture service
guarantees the chemical stability and the
microbiological quality of the ready-to-use
injectable drugs and contributes to the quality and
the total management of the care of the patient
• Since 1996, the centralized preparation of I.V.
medications is a prerequisite for JCI accreditation*
 Project scope
• Hospital Based IV & other fluid production–
Anteneh, Muluken, Mahdi, Kamil, Mengistab
• Sterilized IV admixture– Bereket, Solomon,
Samuel, Seid, Ashenafi
• Non-sterile compounding (Dermatological
preparations & Hand-rub)—Dereje, Sufyan,
Yidne
 WHY CIPAS
• Local production may play an important role,
especially in the long run:-
– Ensure access and availability
– Reduce cost and
– Dependence on other countries,
– Enhancing self-reliance and reaching as many people
as possible.
• To make the best use of limited resources and ban
useless, dangerous and overpriced drugs,
implementation of the CIPAS concept is crucial.
 WHY…
• Reduce the contamination rate
• Decrease medication incidents
• Preparing TPN preparations important for
critical patients
• Improve medication efficacy and reduce dose
errors
• Pediatric dosage admixture
 Objective
The general/main objective of TWG is to
conduct feasibility study of CIPAS
 MEMBERSHIP
• PMED
• AAU
• CHAI
• GHSC-PSM
• EPA
• Hospitals (St.peter & Yekatit)
• FMOH-Infrastructure directorate
• Note: Additional members will be identified and
invited by members of the committee.
 Next step
• Desk review
• Previous site
• Experience sharing
• Checklist development
• Conduct assessment
• Report
Thank You