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JAPANESE
ENCEPHALITIS
BRYANANDA
1670121049
SGD 6
TABLE OF CONTENTS
About Japanese Encephalitis (JE)
Clinical Features
Vaccines
ABOUT JAPANASE ENCEPHALITIS
• A mosquito-borne flavivirus infection, is the leading • JEV is transmitted in an enzootic cycle between
recognized cause of childhood encephalitis in Asia mosquitoes and vertebrate hosts, mainly pigs
and wading birds.
• JE virus (JEV) is a single- • Overall, humans are incidental or dead-end
stranded RNA virus that hosts in the JEV transmission cycle.
belongs to the genus
Flavivirus and is
transmitted to humans
through the bite of an
infected mosquito,
primarily Culex species.
• Fortunately, it cannot
spread directly from
person to person.
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JAPANESE
ENCEPHALITIS
RISK AREAS
4
CLINICAL FEATURES
• Early Symptoms
• Lethargy
• Fever
• Headache
• Abdominal pain
• Nausea
• Vomiting
• Prodormal Symptoms
• Mental changes
• Focal neurological deficits
• Movement disorders
• Generalized weakness
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RISK &
PROTECTIVE
FACTORS
6
PREVENTION WHEN
TRAVELING TO JE RISK AREAS
7
JAPANESE ENCEPHALITIS VACCINE
8
JAPANESE ENCEPHALITIS
VACCINE
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REFERENCES
• CDC. (2018). Japanese Encephalitis Home - Prevention. Centers of Disease Control and Prevention
(Link: https://www.cdc.gov/japaneseencephalitis/prevention/index.html, Accessed on 18
September 2018)
• Chen, H. L., Chang, J. K., & Tang, R. Bin. (2015). Current recommendations for the Japanese
encephalitis vaccine. Journal of the Chinese Medical Association, 78(5), 271–275.
https://doi.org/10.1016/j.jcma.2014.12.009
• Griffiths, M. J., Turtle, L., & Solomon, T. (2014). Japanese encephalitis virus infection. Handbook of
Clinical Neurology (1st ed., Vol. 123). Elsevier B.V. https://doi.org/10.1016/B978-0-444-53488-
0.00026-2
• Halstead, S. B., Hills, S. L., & Dubischar, K. (2018). 33 - Japanese Encephalitis Vaccines. Plotkin’s
Vaccines (Seventh Edition) (Seventh Ed). Elsevier Inc. https://doi.org/https://doi.org/10.1016/B978-
0-323-35761-6.00033-X
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