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  • Spin-Spin Splitting

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    18UGBT055 Surya Prabha
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    Spin-spin coupling, also known as hyperfine splitting, describes the magnetic interactions between neighboring NMR-active nuclei. When this occurs, the signal from equivalent protons on a carbon will split into a multiplet. For example, a methyl group (-CH3) will appear as a triplet, while a methylene group (-CH2-) will show up as a quartet due to spin-spin coupling with the methyl group. This document provides examples of spin-spin coupling in molecules like propane, propanol, isopropanol, glycine, and alanine.

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    5. Spin-spin splitting

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    Spin-spin coupling, also known as hyperfine splitting, describes the magnetic interactions between neighboring NMR-active nuclei. When this occurs, the signal from equivalent protons on a carbon will split into a multiplet. For example, a methyl group (-CH3) will appear as a triplet, while a methylene group (-CH2-) will show up as a quartet due to spin-spin coupling with the methyl group. This document provides examples of spin-spin coupling in molecules like propane, propanol, isopropanol, glycine, and alanine.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    8 views11 pages

    Spin-Spin Splitting

    Uploaded by

    18UGBT055 Surya Prabha
    Spin-spin coupling, also known as hyperfine splitting, describes the magnetic interactions between neighboring NMR-active nuclei. When this occurs, the signal from equivalent protons on a carbon will split into a multiplet. For example, a methyl group (-CH3) will appear as a triplet, while a methylene group (-CH2-) will show up as a quartet due to spin-spin coupling with the methyl group. This document provides examples of spin-spin coupling in molecules like propane, propanol, isopropanol, glycine, and alanine.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 11

    Spin-spin coupling Chemical Biology Research Group

    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 1


    Chemical Biology Research Group

    Spin-spin coupling or Hyperfine Splitting


    Spin-spin coupling describes the magnetic interactions
    between neighboring, non-equivalent NMR-active nuclei.

    Each set of equivalent hydrogens on a given carbon


    is split into an n+1 multiplet by adjacent hydrogen atoms that
    are nonequivalent to the hydrogens of the given carbon

    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 2


    Chemical Biology Research Group

    “a" group of protons signal consisting of a cluster of three peaks (triplet)

    “b” group of protons consists of a cluster of four peaks (quartet)


    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 3
    Chemical Biology Research Group

    Why have the signals split?


    The spin of (-CH3) can couple with the nearby
    methylene group in three distinct ways in relation to
    the external field.

    Triplet signal is given by -CH3


    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 4
    Chemical Biology Research Group

    The spin of (-CH2) can couple with the nearby methyl


    group in four distinct ways in relation to the external
    field.

    Quartet signal is given by –CH2


    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 5
    Chemical Biology Research Group

    Trichloroethane

    N+1

    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 6


    Chemical Biology Research Group

    CH3-CH2-CH3 - propane Ha – 3 triplet


    a b a
    Hb – 7, heptet

    1.37 a

    0.91 0.91

    2 1 0
    PPM

    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 7


    Chemical Biology Research Group

    CH3-CH2-CH2-OH - propanol
    c b a Ha – 3, triplet
    Hb – 6, Hextet
    Hc – 3, triplet

    c
    a
    b

    3 2 1 0
    PPM
    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 8
    Chemical Biology Research Group

    CH3-CH-CH3 - Isopropanol
    OH

    3 2 1 0
    PPM

    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 9


    Chemical Biology Research Group

    O Glycine

    H2N CH C OH

    10 8 6 4 2 0
    PPM
    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 10
    Chemical Biology Research Group

    Alanine
    H2N CH C OH

    CH3

    3.67
    H2N OH

    1.23

    10 8 6 4 2 0
    PPM

    Monday, January 17, 2022 anbazhagan@scbt.sastra.edu 11

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