Antacids

By:
Isha Rani
Assistant Professor MMCP,
MMU- Mullana
 Antacids
Antacids

“The substance which neutralizes excess amount of

acid in gastrointestinal tract is called as antacid”
e.g: Sodium bicarbonate (NaHCO3), Magnesium
hydroxide Mg(OH)2
 Ideal Properties of Antacids
Should not be absorbable
Fine particle size
Should not cause constipation
Should not cause systemic alkalosis
Should not act as laxative
Readily available
Should not produce large volume of gas
Non toxic
 Types of Antacids
Antacids are two types:

Systemic (absorbable) Antacid: which are soluble,

readily absorbable and producing alkalosis e.g.
Sodium bicarbonate

Non- Systemic (non-absorbable) Antacid: which are

not absorbable and not produced systemic effect.
Non systemic antacids divided as
• Aluminium containing antacids: Aluminium
phosphate, Aluminium hydroxide
• Calcium containing antacids: Calcium carbonate,
tribasic calcium phosphate
• Magnesium containing antacids: Magnesium
carbonate, magnesium hydroxide
• Combination antacids: Aluminium hydroxide gel and
magnesium hydroxide