PRINCIPLES

OF PHARMACEUTICAL PROCESSING
Milling (Size Reduction)
Importance of size Reduction in Pharmacy:
Particle Size Reduction Mechanisms
A flaw in a unit particle is a discontinuity or imperfection in the
structure
Classification of size Reduction equipment
 Intermediate Crushing
Hammer Mill
A, rotating disc; B, shaft; c, hammers; D, breaker plates; E, screen
CUTTING MILL
EDGE AND END RUNNER MILLS
EDGE AND END RUNNER MILLS
 Fine Crushers
Fluid Energy Mill
Schematic of fluid energy mill and particle collection system
Ball Mill
Ball Mill
Batch
 Ball Mill
Continuous
 Ball Mill
Continuous closed - circuit milling
Oscillating Granulator
Colloid mills