GOOD AFTERNOON!!

HYDROGEN
BONDING
WHAT IS HYDROGEN BONDING?

• Hydrogen bonding is a special type of dipole-dipole

attraction between molecules, not a covalent bond to a
hydrogen atom. It results from the attractive force
between a hydrogen atom covalently bonded to a very
electronegative atom such as a N, O, or F atom and
another very electronegative atom
• Hydrogen bonding, interaction involving a hydrogen atom located
between a pair of other atoms having a high affinity for electrons;
such a bond is weaker than an ionic bond or covalent bond but
stronger than van der Waals forces. Hydrogen bonds can exist
between atoms in different molecules or in parts of the same
molecule. One atom of the pair (the donor), generally a fluorine,
nitrogen, or oxygen atom, is covalently bonded to a hydrogen
atom (―FH, ―NH, or ―OH), whose electrons it shares
unequally; its high electron affinity causes the hydrogen to take on
a slight positive charge.
• The other atom of the pair, also typically F, N, or O, has an unshared electron
pair, which gives it a slight negative charge. Mainly through electrostatic
attraction, the donor atom effectively shares its hydrogen with the acceptor
atom, forming a bond. Because of its extensive hydrogen bonding, water
(H2O) is liquid over a far greater range of temperatures that would be
expected for a molecule of its size. Water is also a good solvent for ionic
compounds and many others because it readily forms hydrogen bonds with
the solute. Hydrogen bonding between amino acids in a linear protein
molecule determines the way it folds up into its functional configuration.
Hydrogen bonds between nitrogenous bases in nucleotides on the two strands
of DNA (guanine pairs with cytosine, adenine with thymine) give rise to the
double-helix structure that is crucial to the transmission of genetic
information.
HYDROGEN BONDING FIGURE:
PROPERTIES OF HYDROGEN BONDING

• Solubility – Because of the hydrogen bonding that can

occur between water and the alcohol molecule, lower
alcohols are soluble in water. The lower density of ice
than water – In the case of solid ice, hydrogen bonding
causes water molecules to form a cage-like structure.
 WHY HYDROGEN BONDS FORM?

The reason hydrogen bonding occurs is because the electron is

not shared evenly between a hydrogen atom and a negatively
charged atom. Hydrogen in a bond still only has one electron,
while it takes two electrons for a stable electron pair
A hydrogen bond is formed when the positive end of
one molecule is attracted to the negative end of
another. The concept is similar to magnetic attraction
where opposite poles attract. Hydrogen has one
proton and one electron. This makes hydrogen an
electrically positive atom because it has a deficiency
of electrons.
IMPORTANCE OF HYDROGEN
BONDING
Hydrogen bonding is important in many chemical
processes. Hydrogen bonding is responsible for water’s
unique solvent capabilities. Hydrogen bonds hold
complementary strands of DNA together, and they are
responsible for determining the three-dimensional structure
of folded proteins including enzymes and antibodies.
Hydrogen bonds are extremely important in biology, as
they are the reason for the structure of DNA and its
properties. These bonds are responsible for the connections
between the two strands of DNA between the nucleotide
base pairs.
TYPES OF HYDROGEN BONDING.

Intramolecular hydrogen bonding.

• Intermolecular hydrogen bonding.