Which cytokine is thought to play a greater role in

the pathophysiologic process of Crohn’s disease

versus ulcerative colitis?
A)Interleukin-4
B)a4-integrin
C)TNF-a
D)HLA-DR2
• C)TNF-a
• Which of the following is more characteristic
of ulcerative colitis than Crohn’s disease?
• A)Confinement of disease to the colon and
rectum
• B)Fistula formation
• C)Cobblestone pattern of inflammation
• D)Extension of inflammation below the
intestinal mucosa
• A)Confinement of disease to the colon and
rectum
• A patient who had visited the pharmacy query
about the
• 1. nutritional therapy receiving long-term
sulfasalazine therapy?
• A)Vitamin C
• B)Vitamin K
• C)Folic acid
• D)Zinc
• B)Vitamin K
Hepatotoxicity (some cases were fatal), including
elevated liver function tests (SGOT/AST, SGPT/ALT,
GGT, LDH, alkaline phosphatase, bilirubin), jaundice
, cholestatic jaundice, cirrhosis, cholestatic hepatitis,
cholestasis, possible hepatocellular damage
(including liver necrosis and liver failure); Kawasaki-
like syndrome with hepatic function changes;
fulminant hepatitis; hepatitis; hepatic failure[Ref]
• Which of the following drugs would be the
most effective for induction of remission of
active ulcerative proctitis?
• A)Oral mesalamine
• B)Mesalamine suppository
• C)Oral azathioprine
• D)Intravenous infliximab
• B)Mesalamine suppository
• Which drug has been shown to have
corticosteroid sparing properties when used
for treatment of ulcerative colitis?
• A)Mercaptopurine
• B)Sulfasalazine
• C)Mesalamine
• D)Balsalazide
• A)Mercaptopurine
• Which one of the following is a potential
adverse effect of infliximab?
• A)Pancreatitis
• B)Leukopenia
• C)Secretory diarrhea
• D)Infection
• D)Infection
• What is a potential role for the use of metronidazole
in patients with inflammatory bowel disease?
• A)Alternate first line therapy for mild active
ulcerative colitis
• B)Maintenance therapy for moderate active
ulcerative proctitis
• C)Treatment of perianal or fistulizing Crohn’s disease
• D)No role in the treatment of inflammatory bowel
disease
• C)Treatment of perianal or fistulizing Crohn’s
disease
• Which drug would be the best initial therapy
for acute treatment of a hospitalized patient
with severe active Crohn’s disease who has
failed maximum oral doses of mesalamine?
• A)Intravenous methylprednisolone
• B)Intravenous cyclosporine
• C)Oral olsalazine
• D)Oral azathioprine
• A)Intravenous methylprednisolone
•
Which baseline diagnostic test should be
performed prior to initiating infliximab
therapy?
• A)Serum potassium
• B)Tuberculin skin test
• C)Thyroid stimulating hormone
• D)Urinalysis
• B)Tuberculin skin test
• Which one of the following medications would
be most appropriate as initial treatment of
mild to moderate active Crohn’s disease
involving the terminal ileum?
• A)Mesalamine (Rowasa enema)
• B)Olsalazine sodium (Dipentum)
• C)Balsalazide sodium (Colazal)
• D)5-Aminosalicylic acid (Pentasa)
• D)5-Aminosalicylic acid (Pentasa)
• Which medication is most effective for
treatment of fistulizing Crohn’s disease?
• A)Sulfasalazine
• B)Ciprofloxacin
• C)Infliximab
• D)Methotrexate
• C)Infliximab
• Which one of the following medications would
be the most appropriate to treat an acute flare
of distal ulcerative colitis in a patient who is 17
weeks pregnant?
• A)Azathioprine
• B)Methotrexate
• C)Budesonide
• D)Prednisone
• D)Prednisone
•
Which one of the following drugs should not be
used as maintenance therapy in a patient with
Crohn’s disease?
• A)Prednisone
• B)Methotrexate
• C)Infliximab
• D)Azathioprine
• A)Prednisone
• Which of the following drugs would be
preferred to treat a patient with fistulizing
Crohn’s disease (CD)?
• A)Mesalamine
• B)Infliximab
• C)Balsalazide
• D)Methotrexate
• B)Infliximab
• Which one of the following is an adverse
effect of azathioprine?
• A)Pancreatitis
• B)Pulmonary fibrosis
• C)Secretory diarrhea
• D)Hyperglycemia
• A)Pancreatitis
• Loperamide should be avoided in patients
with active ulcerative colitis (UC) due to its
ability to induce which one of the following
complications?
• A)Toxic megacolon
• B)Intestinal stricture
• C)Fistula formation
• D)Pancreatitis
• A)Toxic megacolon
• Which one of the following antibiotics may be
useful as adjunctive therapy in patients with
perianal CD?
• A)Clindamycin
• B)Amoxicillin
• C)Metronidazole
• D)Rifampin
• C)Metronidazole
• Which one of the following medications would
be contraindicated in a pregnant patient with
CD?
• A)Sulfasalazine
• B)Budesonide
• C)Infliximab
• D)Methotrexate
• D)Methotrexate
• Which one of the following disorders is a
possible extraintestinal manifestation of
inflammatory bowel disease?
• A)Erythema nodosum
• B)Peptic ulcer disease
• C)Asthma
• D)Sinusitis
• A)Erythema nodosum
• Natalizumab’s mechanism of action can best
be characterized as a:
• A)TNF-a inhibitor
• B)Purine antagonist
• C)Folate antagonist
• D)Leukocyte adhesion inhibitor
• D)Leukocyte adhesion inhibitor
• A pregnant patient who is receiving
sulfasalazine should also receive supplemental
• :A)Vitamin D
• B)Vitamin A
• C)Folic acid
• D)Iron
• C)Folic acid
• Patients receiving the MMX multi matrix
formulation of mesalamine should be
instructed to
• :A)Divide the total daily dose into 2 or 3 doses
• B)Not crush the tablet to make it easier to
swallow
• C)Avoid taking the drug with dairy products
• D)Take a total of 1.2 g/day for moderately
active disease
• B)Not crush the tablet to make it easier to
swallow
• Which medication should not be used for
maintenance therapy of UC?
• A)Prednisone
• B)Azathioprine
• C)Mesalamine
• D)Infliximab
• A)Prednisone
• Which condition may develop with the use of
infliximab in elderly patients?
• A)Progressive multifocal leukoencephalopathy
• B)Hypertension
• C)Seizures
• D)Heart failure
• D)Heart failure
• Which best describes the role of methotrexate
in the treatment of CD?
• A)First-line treatment for fistulizing disease
• B)Maintenance therapy for corticosteroid-
dependent patients
• C)First-line treatment for pregnant patients
• D)No role, as it is only indicated in the
treatment of UC
• A)First-line treatment for fistulizing disease
• Which of the following is more commonly
associated with CD rather than UC?
• A)Superficial colonic inflammation
• B)Proctitis
• C)Fistula formation
• D)Continuous colonic inflammation
• C)Fistula formation
• I take sazo 500 2 tabs bd for UC. Today I
want to take cifran 500 1 tab bd for my
upset stomach. Does it go with sazo?
• A PT dilutes a 1g vial of cefazol to 100mL
which solution should the PT use for a
compound dose of 500mL?
• 5ML
• Which of the following is the maximum
number of times a Rx for C3 and C4
medication can be refilled within six months
from the date it was originally written

• Five times within six months

• According to Federal Law which of the
following is a C2 medication?
• Cocaine - C2
Heroin, Marijuana, Mescaline - C1
• What is the error in this Rx?

Glimepiride (Amaryl) 2.0mg one tablet orally

once daily #90
• The strength of 2.0mg should be written as
2mg
• A Pharmacy Technician should ID that which
of the following volumes is equal to 45mL

• 3 TAB SPOON
• How many tablets should the Pharmacy
Technician dispense?

Sulfasalazine 500mg tabs 1.5g qid x 10d

• 120 TABS
• When no pharmacist is on duty...

• A sign must be posted on the prescription

counter and on all entrance doors informing
the public