Chlorpheniramine

MD. Sakib Talukder

2011945649
 Introduction

• Chlorpheniramine is an antihistamine medication

used to treat allergy symptoms.

• It is a first-generation antihistamine, blocking the

effects of histamine released during an allergic
reaction.
 Classification

Traditionally, H1 antihistamines have been classified into 6 chemical groups:

 Mechanism of Action

Chlorpheniramine binds to the histamine H1

receptor. This blocks the action of endogenous
histamine, which subsequently leads to
temporary relief of the negative symptoms
brought on by histamine.
 Indications

It is used for the treatment of -

• Rhinitis,
• Urticaria,
• Allergy,
• Common cold,
• Asthma and
• Hay fever.
 Dosage and Administration

Usual Adult Dose for Allergic Rhinitis -

• 4 mg oral tablets: 1 tablet orally every 4 to 6 hours

Maximum dose: 6 tablets per 24 hours

• 12 mg extended release tablets : 1 tablet every 12 hours

Maximum dose: 2 tablets per 24 hours

• 2 mg/ 5 mL syrup: 10 mL orally every 4 to 6 hours

Maximum dose: 6 doses per 24 hours
 Side Effects

Common side effects -

• Feeling sleepy during the daytime,

• Feeling sick (nausea),
• Feeling dizzy or difficulty concentrating,
• Dry mouth,
• Headaches and
• Blurred vision.
 Conclusion

Chlorpheniramine is a first-generation antihistamine used to treat allergies and

related symptoms. It works by blocking histamine effects in the body. It is
effective in treating allergic rhinitis, hay fever, itching, and common cold
symptoms. However, it can cause side effects such as drowsiness and dry mouth.
Proper dosage and following healthcare professional's instructions are important.
Special precautions may be necessary for specific populations. Overall,
Chlorpheniramine is a valuable tool for managing allergy symptoms.
Thank you !