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  • Antitussive Drugs

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    Laghari Jamil
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    Cough is a normal reflex to clear irritants from the lungs and airways. Dry cough needs to be suppressed, while productive cough should be promoted. Codeine suppresses the cough reflex through mu opioid receptors but can cause drowsiness and dizziness. Dextromethorphan is an antitussive that acts as an NMDA receptor antagonist but may cause hallucinations. Antihistamines like chlorpheniramine can manage cough symptoms from allergies but often cause sleepiness, dizziness, dry mouth and blurred vision as side effects.

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    Cough is a normal reflex to clear irritants from the lungs and airways. Dry cough needs to be suppressed, while productive cough should be promoted. Codeine suppresses the cough reflex through mu opioid receptors but can cause drowsiness and dizziness. Dextromethorphan is an antitussive that acts as an NMDA receptor antagonist but may cause hallucinations. Antihistamines like chlorpheniramine can manage cough symptoms from allergies but often cause sleepiness, dizziness, dry mouth and blurred vision as side effects.

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    3 views7 pages

    Antitussive Drugs

    Uploaded by

    Laghari Jamil
    Cough is a normal reflex to clear irritants from the lungs and airways. Dry cough needs to be suppressed, while productive cough should be promoted. Codeine suppresses the cough reflex through mu opioid receptors but can cause drowsiness and dizziness. Dextromethorphan is an antitussive that acts as an NMDA receptor antagonist but may cause hallucinations. Antihistamines like chlorpheniramine can manage cough symptoms from allergies but often cause sleepiness, dizziness, dry mouth and blurred vision as side effects.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 7

    Antitussive

    Drugs for dry cough


    Cough

    • Cough is normal physiological reflex action to irritants in larynx ,trachea or in

    bronchus

    • Its not a disease but symptom of diseases.

    • Dry cough need to be suppressed

    • Productive cough need to promoted


    Codeine  

    • It is an opioid, selective agonist for the mu opioid receptors.

    • Codeine suppresses the cough reflex through a direct effect on the


    cough center in the medulla.

    • Side effects : unusual lightheadedness, severe drowsiness/dizziness,


    difficulty waking up
    Dextromethorphan 

    • It is an NMDA receptor antagonist used to treat cases of dry cough.

    • It causes dissociate hallucinogen

    • A dextromethorphan overdose may present as nausea, vomiting,


    stupor, tachycardia.

    • Overdose should be managed through symptomatic and supportive


    measures.
    Antihistamines
    • CHLORPHENIRAMINE
    • It is a histamine-H1 receptor antagonist indicated for the management
    of symptoms associated with upper respiratory allergies.
    • Common side effects
    • feeling sleepy during the daytime.
    • feeling dizzy or difficulty concentrating.
    • dry mouth.
    • headaches.
    • blurred vision.

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