Genetic Disorders

Associated with Meiosis

 TURNER SYNDROME
-underdeveloped ovaries,
uterus, and oviducts
-do not experience
normal ovarian function
-short, broad chest,
webbed neck, and
puffiness or swelling of
hands and feet.
-low posterior hairline
 DOWN SYNDROME
-The most common disorder
of trisomy is Down Syndrome
wherein the 21st chromosome
has three instead of two.
- Short stature, round head,
flat face, slanting eyes, stubby
fingers, wide gap between the
first and second toes, short
neck, short arms, and short
legs
 Klinefelter Syndrome (47, XXY)
• It is a chromosomal abnormality
affecting the physical and
cognitive development of males.
• Underdeveloped prostate gland
and testes
• Lack of facial and body hair, breast
enlargement, unusual small penis
• Males have big hands and feet,
unusual long arms and legs.
• Delayed speech and language
development, learning disabilities.
 Klinefelter Syndrome
• Some variants of
Klinefelter have
more than one extra
chromosome in
each cell such as in
48, XXXY or 49,
XXXXY that are
associated with
severe form of
abnormality.
 TRISOMY X (XXX)
• The abnormal presence of
an extra X chromosome is
also known as Trisomy X
syndrome, which affects
1/1000 in females.
• Affected individuals
usually have mild
symptoms or none at all.
• Delays and language-
based learning disabilities