Quality Management in

Rapid Diagnostic Testing

Dr. dr. Efrida, Sp.PK (K), M.Kes

 HIV DISEASE
INTRODUCTION BACKGROUND AND
01 What HIV is
03 EPIDEMILOGY

EARLY DETECTION HIV TESTING

02 Window periode of infection
04 How to diagnose HIV
 Introduction

Human immunodeficiency virus (HIV) is a retrovirus that causes a chronic

infection in the cells of the immune system. It is transmitted via exposure
to body fluids containing free virus particles. Without treatment, most
persons with HIV develop acquired immunodeficiency syNdrome (AIDS)
within 10 years infection, which is associated with substansial morbidity
and premature death.
Picture 1. HIV structure
WINDOW PERIOD OF INFECTION
 01
HIV
TESTING
TYPES OF HIV DIAGNOSTIC TEST

SEROLOGICAL OTHER
ASSAYS COMMERCIAL
• First generstion ALTERNATIVES
• Second generation Home testing kits :
• Third generation • Instant result self-testing kits
• Fourth generation • Home sampling kits
Table 2. Generation of HIV Serology Assays
Table 3. Assay format of HIV in vitro diagnostics and their operational characteristics
PEMERIKSAAN HIV
Prinsip Pemeriksaan HIV dengan Rapid Test
Figure 2. HIV Screening
HIV Confirmation