Impact des facteurs environnementaux sur les paramètres spermatiques d’une

population du centre et de l’ouest d’Algérie : étude prospective et génétique

 Plan de travail

Introduction objectif Généralité

Matériels Résultats
et et Conclusion
méthodes discussion
 01
Introduction
 1/ Introduction
• L'infertilité humaine devient un problème de santé publique
• Infertilité = l'échec à obtenir une grossesse clinique après 12 mois ou plus de RS réguliers
en absence de contraception chez un couple en âge de procrée

Origine 15% des Origine mixte

masculine 20% couples 40%

60% l’homme a des difficulté de

concevoir

Deux types d’infertilité Infertilité primaire

Infertilité secondaire
Les facteurs de risques impliqués dans l’infertilité
masculine

Facteurs environnementaux Les polluants atmosphérique, les

perturbateurs endocriniens, les
pesticides, les métaux lourds…..ets

Facteurs liées aux mode de vie Le tabagisme, l’alcool, drogues, obésité, bains chaud
…..ets

Facteurs génétiques Anomalies chromosomiques, les mutations géniques, les

polymorphismes génique (syndrome de klinefelter, MCY)

L’appareil reproducteur masculin Détérioration de la qualité du sperme

 02
objectifs
2/ Objectifs :
Notre étude consiste à:

Évaluer l’effet de l’un des facteurs de risques comportementaux qui est le fumer du
tabac sur la qualité du sperme et évaluer sa vrai place dans l’infertilité du couple

Déterminer la fréquence des différentes anomalies du spermogramme et

Spermocytogramme chez la population étudiée

Réaliser l’exploration moléculaire chez les hommes présentant des

anomalies sévères de la spermatogenèse, en déterminant une
éventuelle microdélétion du chromosome Y

Déterminer la fréquence de ces microdélétion dans une

population de l’Ouest Algérien et la prise en charge en PMA
 03
généralité
BACKGROUND

MERCURY MARS JUPITER

Mercury is the Despite being red, It’s the biggest
smallest planet Mars is cold planet

VENUS SATURN EARTH

Venus has a Saturn is a gas giant Earth is the planet
beautiful name and has rings we live on
GOALS

MERCURY VENUS MARS

Mercury is the Venus is the second Despite being red,

closest planet to the planet from the Sun Mars is actually a
Sun cold place
METHODS

OBSERVATION DATA COLLECTION

Mercury is the Saturn is a gas giant
smallest planet and has rings

HYPOTHESIS REPORT
Venus is the second Earth is the planet we
planet from the Sun live on
RESEARCH AND PUBLICATIONS

“Venus has a beautiful “Despite being red, Mars is

name and is the second A cold place. It’s full of
planet from the Sun. It’s iron oxide dust, which
terribly hot, even hotter gives the planet its
than Mercury” REDDISH cast”

By Venus By Mars
RESEARCH RESOURCES

● Here you can list your reference websites or publications

● Here you can list your reference websites or publications
● Here you can list your reference websites or publications
● Here you can list your reference websites or publications
● Here you can list your reference websites or publications
FACTORS TO CONSIDER

RISK FACTORS OF GENETIC

ALTERATION

● List here the risk factors

● List here the risk factors
● List here the risk factors
● List here the risk factors
● List here the risk factors
● List here the risk factors
CLINICAL TRIAL

PRECLINICAL PHASE 1 PHASE 2 PHASE 3

Lab Studies Human Safety Expanded Safety Efficacy & Safety

TRIAL TIMELINE

WEEK 4
04
Earth is the planet we live on

WEEK 3
03
Mercury is the smallest planet

WEEK 2
02
Mars is actually a cold place

WEEK 1 01
Venus has a beautiful name
PHASE 1

Sample Results

Result 1
Result 2
Result 3

70% 30% Result 4

Experimentation time

January April July

TENDENCY

1-10 years

11-25 years

26-40 years

41-60 years

60+ years

To modify this graph, click on it, follow

the link, change the data and paste the
resulting graph here
A PICTURE IS
WORTH A
THOUSAND
WORDS
RESULTS

Experiment 1 Experiment 2

Treatment Test 1 Test 2 Test 3 Treatment Test 1 Test 2 Test 3

Group 1 242 135 677 Group 1 765 322 113

Group 2 761 435 453 Group 2 434 546 666

Group 3 746 353 555 Group 3 975 356 354

RESULTS ANALYSIS

30% 32,000
Venus has a beautiful name,
but it’s terribly hot

50%

677,000
80%
Despite being red, Mars is
actually a cold place
OUR FIELD OF STUDY

Jupiter is a gas giant,

the biggest planet in
the Solar System and
the fourth-brightest
object in the sky. It
was named after the
Roman god of the sky
and lightning
 75.50%
This the success rate according to the data gathered during the
study
 CONCLUSIONS

Mercury is the closest planet to the Sun

and the smallest one in the Solar
System—it’s only a bit larger than our
Moon. The planet’s name has nothing
to do with the liquid metal since
Mercury was named after the Roman
messenger god
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