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  • Folding of Embryo1

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    Akinrotimi Oluwadunsin
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    Folding occurs as the embryo develops due to uneven growth rates in different regions. This results in longitudinal folding which produces head and tail folding, as well as lateral folding. Head folding causes the cranial region to move ventrally, positioning the developing brain and heart. Tail folding moves the caudal region ventrally, forming the hindgut and cloaca. Lateral folding occurs due to growth of the spinal cord and somites, rolling the lateral edges of the embryo ventrally and fusing them to form a cylinder. This creates the midgut and connecting stalk between embryo and extraembryonic tissues.

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    Folding of embryo1

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    Folding occurs as the embryo develops due to uneven growth rates in different regions. This results in longitudinal folding which produces head and tail folding, as well as lateral folding. Head folding causes the cranial region to move ventrally, positioning the developing brain and heart. Tail folding moves the caudal region ventrally, forming the hindgut and cloaca. Lateral folding occurs due to growth of the spinal cord and somites, rolling the lateral edges of the embryo ventrally and fusing them to form a cylinder. This creates the midgut and connecting stalk between embryo and extraembryonic tissues.

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    © All Rights Reserved
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    2 views15 pages

    Folding of Embryo1

    Uploaded by

    Akinrotimi Oluwadunsin
    Folding occurs as the embryo develops due to uneven growth rates in different regions. This results in longitudinal folding which produces head and tail folding, as well as lateral folding. Head folding causes the cranial region to move ventrally, positioning the developing brain and heart. Tail folding moves the caudal region ventrally, forming the hindgut and cloaca. Lateral folding occurs due to growth of the spinal cord and somites, rolling the lateral edges of the embryo ventrally and fusing them to form a cylinder. This creates the midgut and connecting stalk between embryo and extraembryonic tissues.

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    © All Rights Reserved
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    of 15

    FOLDING

    ANATOMY 205
    BY
    Dr Ibitoye B. O
    OUTLINE
    • Introduction
    • Folding in median plain/longitudinal folding
    • Head Folding
    • Effect of Head Folding
    • Tail Folding and effect
    • Folding in Horizontal plane/Lateral folding
    • Effects of lateral folding
    Introduction
    • FOLDING is an event that brings about conversion of trilaminar
    embryonic disc to cylindrical embryo and somewhat definitive human
    shape
    • Folding result from geometrical growth of the embryo in some region
    compare to some region. The growth rate is not uniform in every part
    of the embryo, more the cranio-caudal axis
    • The folding occur concurrent in the cranio-caudal axis(median plane)
    and horizontal axis(plane) bringing head & tail folding and lateral
    folding
    FOLDING IN MEDIAN
    PLAIN/Longitudinal folding
    • Folding in this plain produces
    Head and tail folding
    In head folding, the cranial region move ventrally
    While in tail folding the caudal region move also ventrally
    Head Folding
    • This and other folding starts at the beginning of the fourth week

    • The developing brain grow rapidly beyond oropharyngeal membrane


    thereby overhangs the primordial heart.
    Effect of Head Folding
    • The following structures move anteriorly
    Septum transversum and caudal to the heart
    Primordial heart
    Pericardiac coelom(now ventral to the heart)
    Oropharyngeal membrane
    • New structure formed
    Foregut from yolk sac endoderm
    Tail Folding and effect

    • Result from growth of distal part of the neural tube


    • EFFECTS
    Formation of hindgut and subsequently cloaca
    Primitive streak lie caudal to cloacal membrane
    Allantois and connecting stalk is ventral
    Folding in Horizontal plane/Lateral folding
    • This result from rapid growth of spinal cord and formation of somites

    • This folding create a cylindrical embryo by rolling of the embryonic


    lateral extremes ventrally

    • Final fusion of the lateral edges reduces the link between


    intraembryonic and extraembryonic coelom
    Effects of lateral folding
    • Formation of midgut

    • Formation of the connecting stalk


    Folding in the two planes
    THANK YOU

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