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ANEMIA • PRESENTED BY:

• SADIA MOIN (10527)


PRESENTED TO:
SIR AMJAD JAMI
INTRODUCTION

• Anemia is a major killer in India.


• Statistics reveal that every second Indian woman are anemic.
• One in every five maternal deaths is directly due to anemia.
• Anemia affects both adults and children of both sexes, although pregnant women and
adolescent girls are most susceptible and most affected by this disease.
OBJECTIVES
• Definition of anemia.
• Types of anemia.
• Anemia causes.
• Anemia symptoms.
• Lab investigation of anemia.
• Treatment.
• Prevention.
DEFINITION
• Anemias are generally a sign of underlying pathology; therefore, determining the cause of the
anemia is important.

• Possible consequences of chronic anemia include reduced quality-of-life, decreased survival,


and increased risk of cardiac complications, neurologic dysfunction, and surgical
complications.

• Awareness of anemia, its detection, investigation and management must be raised.


CLINICAL PRESENTATION OF ANEMIA

• Patients may be asymptomatic or have vague complaints.


• Patients with vitamin B12 deficiency may develop neurologic consequences.
• In anemia of chronic disease, signs and symptoms of the underlying disorder often overshadow
those of the anemia.
TYPES OF ANEMIA
CAUSES OF ANEMIA

• Production defects
• Maturation defects
• Survival defects
• Sequestration
• Blood loss
SYMPTOMS OF ANEMIA
• Fatigue
• Headache
• Yellowish skin
• Irregular heartbeats
• Chest pain
• Cold hands
• Dizziness
• Leg cramps
• Insomnia
RISK FACTORS

• Poor socio economic class.


• Multiparity.
• Teenage pregnancy.
• Menstural problem.
INVESTIGATION
THE RED CELL POPULATION IS DEFINED BY :
1. QUANTITATIVE PARAMETERS:

• VOLUME OF PACKED CELLS I.E. THE HEMATOCRIT.


• HEMOGLOBIN CONCENTRATION.
• RED CELL CONCENTRATION PER UNIT VOLUME.
2.QUALITATIVE PARAMETERS:

• MEAN CORPUSCULAR VOLUME.


• MEAN CORPUSCULAR HEMOGLOBIN.
• MEAN CORPUSCULAR HEMOGLOBIN CONCENTRATION.
CONT…..
Hematocrit ( packed cell volume):
It is the proportion of the volume of blood sample that is occupied by rbcs.

• MEN -42-52%
• WOMEN -36-48%
Cell volume hemoglobin concentration:
It is the amount of hemoglobin per unit volume of blood.(gms/dl)

• WOMEN - 12-16GMS/DL
• MEN - 14-17 GMS/DL
Red cell count:
Total number of red cells per unit volume of blood sample. [ no.of rbc/ cu.mm ].

• MEN - 4.2-5.4*106//MM3.

• WOMEN- 3.6-5.0* 106/MM3.


TREATMENT

• General treatment for anemia diet nutritional supplements: e.g.) iron, b12, folic acid treatment of
infection or inflammation erythropoietin- drug to treat low blood cell count (mainly used with
renal patients) blood transfusion bone marrow transplant
GENERAL TREATMENT OF ANEMIA
1. Diet.
2. Nutitional supplements: e.g.) iron, b12, folic acid.
3. Treatment of infection or inflammation.
4. Erythropoietin- a drug to treat low blood cell count (mainly used with renal patients).
5. Blood transfusion.
6. Bone marrow transplant.

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