transgenic animals, their

applications in research
and industry,
environmental safety
concerns, regulations, and
future prospects.
Yassir BOURTAL grp 31
2nd year student <medicine>
DEFINITION:

Transgenic animals are genetically modified organisms that play a crucial role in
various fields, from medical research and drug development to agricultural
improvements.
 Applications of Transgenic Animals

Medical Research and Drug Development Agricultural Improvements

Transgenic animals provide valuable insights Genetically modified animals can enhance
into human diseases and contribute to the livestock productivity, improve food quality, and
development of new treatments and increase resistance to diseases and environmental
therapies. factors.
 The process of transgenic
animal
• Identification of Target Gene: that researchers want to introduce or modify in the animal. This
gene could be from the same species or a different species.
• Isolation of Target Gene: it is isolated from the source organism. This is typically done using
molecular biology techniques such as
• Construction of the Transgene: The isolated gene is then incorporated into a vector, which is a
carrier molecule that facilitates the transfer of the gene into the animal cells. Common vectors
include plasmids or viral vectors.
• Introduction of Transgene into Animal Cells: The transgene, carried by the vector, is
introduced into the reproductive cells (usually fertilized eggs or embryonic stem cells) of the
animal. This can be done through methods such as microinjection.
• Integration into the Genome: The transgene integrates into the genome of the animal's cells.
This integration is crucial for the transgene to be passed on to the animal's offspring during
reproduction.
 Regulations and Ethical
Considerations

regulations and guidelines ensure the

responsible use and ethical treatment of
transgenic animals in research and industry. Ethical Implications and Public
Perception
Public debate and ethical considerations
surround the creation and use of transgenic
animals, influencing public opinion and
determining the acceptability of their
applications
Future Prospects

Emerging gene editing techniques offer

new possibilities for precise genome
modifications in transgenic animals.

Transgenic animals can be engineered to

produce valuable proteins, enzymes, or
other substances in their milk, blood, or
tissues. This has applications in the
pharmaceutical and biotechnology

Transgenic approaches may contribute to

the conservation of endangered species by
addressing genetic diversity
THANKS FOR
YOUR
ATTENTION