Professional Documents
Culture Documents
disorder
Presentor ;Zekariyas A
Natinael B
Alazar M
Rahel M
PRESENTOR:ZEKARIYAS A
outline
• Normal sexuality
• Childhood sexuality
• Psychosexual factors
• CNS and sexual behavior
• Physiologic response
• Gender difference in desire and erotic stimuli
Normal Sexuality
• Sexuality has always been an area of interest to the
medical community in different eras.
• Sexuality is determined by anatomy, physiology, the
culture in which a person lives, relationships with
others, and developmental experiences throughout
the life cycle.
• Normal sexual behavior brings pleasure to oneself
and one’s partner and involves stimulation of the
primary sex organs including coitus
• it is devoid of inappropriate feelings of guilt or
anxiety and is not compulsive.
• Sexuality and total personality are so entwined that
to speak of sexuality as a separate entity is virtually
impossible.
• The term psychosexual applies to more than sexual
feelings and behavior, and it is not synonymous
with libido in the broad Freudian sense
CHILDHOOD SEXUALITY
• Before Freud described the effects of childhood
experiences on personalities of adults, the
universality of sexual activity and sexual learning in
children was unrecognized.
• Most sexual learning experiences in childhood
occur without the parents’ knowledge, but
awareness of a child’s sex does influence parental
behavior
• During a critical period in development, infants are
especially susceptible to certain stimuli;
• later, they may be immune to these stimuli.
• The detailed relation of critical periods to
psychosexual development has yet to be
established;
• Freud’s stages of psychosexual development—
oral, anal, phallic, latent, and genital—presumably
provide a broad framework.
PSYCHOSEXUAL FACTORS
• Sexuality depends on four interrelated
psychosexual factors:
sexual identity,
gender identity,
sexual orientation, and
sexual behavior.
• These factors affect personality, growth,
development, and functioning.
Sexual Identity and Gender
Identity
• Sexual identity is the pattern of a person’s biological
sexual characteristics: chromosomes,
• external genitalia,
• internal genitalia,
• hormonal composition,
• gonads, and
• secondary sex characteristics
• Gender identity is a person’s sense of maleness or
femaleness.
• Sexual identity and gender identity are interactive.
Classification of Intersexual Disordersa
• Turner’s syndrome
• Klinefelter’s syndrome
• Androgen insensetivity syndrome
• Enzymatic defects in XY genotype
• Hermaphroditism
• psedohermaphroditism
Sexual Orientation
• Sexual orientation describes the object of a
person’s sexual impulses:
• heterosexual (opposite sex),
• homosexual (same sex), or
• bisexual (both sexes).
• A group of people have defined themselves as
“asexual” and assert this as a positive identity.
• Some researchers believe this lack of attraction to
any object is a manifestation of a desire disorder.
• Other people wish not to define their sexual
orientation at all and avoid labels. Still others
• describe themselves as polysexual or pansexual.
Sexual Behavior
The Central Nervous System and
Sexual Behavior
THE BRAIN
• Cortex. The cortex is involved both in controlling
sexual impulses and in processing sexual stimuli.
• In studies of young men, some areas of the brain have
been found to be more active during sexual
stimulation than others.
• These include
• the orbitofrontal cortex, which is involved in
emotions;
• the left anterior cingulate cortex, which is involved
in hormone control and sexual arousal; and
• the right caudate nucleus, whose activity is a factor
in whether sexual activity follows arousal.
• Limbic System. In all mammals, the limbic system is
directly involved with elements of sexual functioning.
Chemical or electrical stimulation of
• the lower part of the septum and the contiguous
preoptic area,
• the fimbria of the hippocampus,
• the mammillary bodies, and
• the anterior thalamic nuclei have all elicited penile
erections.
• Studies of the brain in women have revealed that
those areas activated by emotions of fear or anxiety
are notably quiescent when the woman
experiences an orgasm.
• Brainstem. Brainstem sites exert inhibitory and
excitatory control over spinal sexual reflexes.
• Brain Neurotransmitters. Many neurotransmitters,
including dopamine, epinephrine, norepinephrine,
and serotonin, are produced in the brain and affect
sexual function.
• SPINAL CORD. Sexual arousal and climax are
ultimately organized at the spinal level.
• Sensory stimuli related to sexual function are
conveyed via afferents from the pudendal, pelvic,
and hypogastric nerves
Physiological Responses
• Sexual response is a true psychophysiological
experience.
• Arousal is triggered by both psychological and
physical stimuli.
• Psychosexual development, psychological attitudes
toward sexuality, and attitudes toward one’s sexual
partner are directly involved with, and
• affect, the physiology of human sexual response.
• Normally, men and women experience a sequence of
physiological responses to sexual stimulation.
• physiological process involves increasing levels of
vasocongestion and myotonic (tumescence) and the
subsequent release of the vascular activity and
muscle tone as a result of orgasm (detumescence).
• A sexual fantasy or the desire to have sex frequently
precedes the physiological responses of excitement,
orgasm and resolution.
• In addition, a person’s subjective experiences are as
important to sexual satisfaction as the objective
physiologic response.
HORMONES AND SEXUAL
BEHAVIOR
• In general, substances that increase dopamine levels in the
brain increase desire, whereas substances that augment
serotonin decrease desire.
• Testosterone increases libido in both men and women,
although estrogen is a key factor in the lubrication involved
in female arousal and may increase sensitivity in the woman
to stimulation.
• Recent studies indicate that estrogen is also a factor in the
male sexual response and that a decrease in estrogen in the
middle-aged male results in greater fat accumulation just as
it does in women.
• Progesterone mildly depresses desire in men and women as
do excessive prolactin and cortisol. Oxytocin is involved in
pleasurable sensations during sex
GENDER DIFFERENCES IN
DESIRE AND EROTIC STIMULI
• Sexual impulses and desire exist in men and women.
• In measuring desire males generally possess a higher
baseline level of desire than women, which may be
biologically determined.
• Motivations for having sex,other than desire, exist in
both men and women, but seem to be more varied and
prevalent in women.
• In women they may include a wish to reinforce the pair
bond, the need for a feeling of closeness, a way of
preventing the man from straying, or a desire to please
the partner.
• Although explicit sexual fantasies are common to both
sexes, the external stimuli for the fantasies frequently
differ for men and women.
• Many men respond sexually to visual stimuli of nude
or barely dressed women.
• Women report responding sexually to romantic
stories such as a demonstrative hero whose passion
for the heroine impels him toward a lifetime
commitment to her.
Sexual Dysfunctions
29
Introduction
30
Introduction
31
Introduction
Causes can be :
Psychological factors
Physiological factors
Combined factors
Stressors
32
Introduction
Mental disorders causing sexual dysfunction :
Depressive disorders
Anxiety disorders
Personality disorders
Schizophrenia
33
Introduction
34
Introduction
• Sexual dysfunctions are usually self-perpetuating.
35
Divorce: Its cause and impact on the life of
divorced women and children
38
Male Hypoactive Sexual Desire Disorder
39
Male Hypoactive Sexual Desire
Disorder
• Decreased desire isn’t the same to decreased activity.
40
Male Hypoactive Sexual Desire Disorder
41
Etiology
Vagina dentata- Inhibition of desire
Chronic stress, anxiety, or depression
Abstinence from sex for a prolonged period
The sign of a deteriorating relationship
42
43
Female Sexual Interest/Arousal
Disorder
• women do not necessarily move stepwise from
desire to arousal, but often experience desire
synchronously with, or even following, beginning
feelings of arousal.
• women experiencing sexual dysfunction may
experience ,
• either/or both inability to feel interest or arousal, and
• they may often have difficulty achieving orgasm or
experience pain in addition.
44
Epidemiology
45
Etiology
• Hormonal:dopamine, testosterone, estrogen
↑desire
• Serotonine, prolactine ↓desire
• Medication antipsychotic
46
47
48
Evaluation
• A patient’s age
• General health
• Any medication regimen
• Life stresses (cultural norms, Relationship
conflicts)
• A baseline of sexual interest before the
disorder began
• Dx should not be made unless the lack of
desire is a source of distress to a patient.
49
Treatment
• Life style changes
• Psychotherapy
• Treat the possible coexisting illnesses or conditions
50
51
Focus on
• Anatomy and Physiology of erection
• Definition and epidemiology of ED
• Etiology
• Diagnosis
• Treatment
52
Definition
• Male erectile disorder(MED)
• used to called erectile dysfunction/Impotence
• Male erectile disorder is the inability to achieve or
sustain a penile erection sufficient to complete
sexual activity, and the inability must be either
persistent or recurring with the result of marked
distress or problems with interpersonal
relationships
53
Types of male erectile disorder
• Lifelong Vs. Acquired or 20
• Generalized Vs. Situational
• mild, moderate, severe
54
Epidemiology
• Acquired >>>lifelong
• 10 to 20 % of all men
• ED is the chief complaint of > 50% of all men treated for
sexual disorder
• Incidence increases with age
• 2 to 8 % of the young adult population
• 40 to 50 percent in men b/n ages of 60 and 70 while 75
% at age 80
55
Risk factors for acquired ED
Age
Smoking
Exercise,
DM
56
Causes
• Organic(Structural usually in old)
• Psychological (usually in young and middle-aged
men)
• both(majority)
57
Organic Causes of ED
58
Psychological causes
• include current relationship problems, stress,
comorbid with other psychiatric disorders, such as
depression, and anxiety (e.g., guilt, performance
anxiety),personality disorders, and schizophrenia,
• In men with erectile disorder, the presence of
morning erection, erections during masturbation,
or erections during rapid eye movement (REM)
sleep suggests a psychological rather than a
physical cause
59
dx…
Hx
• Onset, duration
• Psychological evaluation_ Comorbidity, substance
• Medical illness, surgery, Drug
PE
• Body habitus BP, Detail examination of
CVS ,Abdomen , Neurology
• External genitalia, DRE(>50yrs)
60
Lab.Diagnostic markers
• Recommended _ FBS, hormone profile, serum lipid
61
62
Dx Criteria DSM-V
A. At least one of the three following symptoms must be
experienced on almost all or all (approximately 75%-100%)
occasions of sexual activity (in identified situational
contexts or, if generalized, in all contexts):
1. Marked difficulty in obtaining an erection during sexual
activity.
2. Marked difficulty in maintaining an erection until the
completion of sexual activity.
3. Marked decrease in erectile rigidity.
63
C .The symptoms in Criterion A cause clinically
significant distress in the individual.
64
Specify whether:
Lifelong: The disturbance has been present since the individual became sexually
active
Specify whether:
Generaiized: Not limited to certain types of stimulation, situations, or partners.
Situational: Only occurs with certain types of stimulation, situations, or partners.
65
Treatment
• Lifestyle modification
• Identify and treat underlining cause
• Therapy for assisted erection
_ psychotherapy+Pharmacologic
66
Psychosexual therapy
• Relaxation techniques, Systematic desensitization
used to reduce anxiety
• Inform regarding sex education, partner
communication,and sexual behavioral therapy
67
Pharmacologic
• First line _ PDE-5 Inhibitors (sildenafil citrate
(Viagra)vardenafil (Levitra, Nuviva) and tadalafil
(Cialis).
_
68
Mechanical ,Surgical
• Second line _Vacuum-assisted erection devices, occlusive rings.
_ Intracorporal injection of vasodilators
• for end stage ED _ penile prosthetic devices
_ penile transplant
69
Vacuum constriction devices
70
Orgasmic disorder
PRESENTOR ;ALAZAR M
outline
• Definition
• Orgasm disorders
• Epidemiology
• Diagnosis
• Treatment approach
Orgasm
• Orgasm is sudden discharge of accumulated sexual
excitement during sexual response cycle resulting in
rhythmic muscular contraction in pelvic region
characterized by sexual pleasure and v/s change.
• Pharmacologic Interventions
• Behavioral interventions
Pharmacologic Interventions
• Topical anesthetics
• Vasculogenic
The most common organic cause of ED
Due to disturbance of blood flow to and from the
penis
DM, dyslipidemia, traumatic, HTN
• Neurogenic
Disorders that affect the sacral spinal cord or the
autonomic nervous system relaxation of penile
smooth muscle, thus leading to ED.
• Spinal cord injury(75%)
• MS
• Neuropathy
• Surgery
Pharmacological Agents
Implicated In Sexual Dysfunction
• Antipsychotic Drugs
• Antidepressant Drugs
• Sympathomimetics
• α-Adrenergic and β-Adrenergic Receptor
Antagonists
• Anticholinergics
• Antihistamines
• Antianxiety Agents
• Alcohol
• Opioids
• Hallucinogens
• Cannabis
• Barbiturates and Similarly Acting Drugs
Treatment
• Sildenafil, Tadalafil, Avanafil
• Treat underlying conditions.
• Removing the offending drug
Female
• Neurologic – stroke, spinal injury, Parkinson's
• Trauma, surgery, radiation
• DM, hyperprolactinemia
• Liver and renal failure
• CVDs
• drugs
PRESENTOR:RAHEL MESERET
Introduction
Paraphilia's/perversions are recurrent, intense, sexually arousing
fantasies, urges, or stimuli that are deviated from normal sexual
behaviors.
Paraphilics do not experience arousal and orgasm to stimuli that
are typically considered erotic.
DSM-5 only considers paraphilia a disorder when
A person has acted on the fantasy or impulse, or
If the fantasies or impulses lead to significant distress.
Resulting in negative consequences or psychosocial impairment.
Epidemiology
Paraphilias are rare, but the insistent, repetitive
nature of the disorders gets attention.
The prevalence may be much higher than that found in
clinical care.
As usually defined, the paraphilias seem to be mostly
male conditions.
More than 50 % of all paraphilias have their onset before
age 18.
The occurrence peaks between ages 15 and 25 and
gradually declines.
Cont…
Paraphiliacs frequently have three to five paraphilias,
either concurrently or at different times in their lives.
Of adult females, 20 % have been the targets of
exhibitionists and voyeurisms.
Among legally identified cases of paraphilic disorders,
pedophilia is most common.
Sexual sadism usually comes to attention only in
sensational cases of rape, brutality, and lust murder.
Etiology
Psychosocial Factors.
Many paraphilias can be traced back to childhood
experiences.
Molestation as a child can predispose to accept
continued abuse as an adult or, conversely, to
become an abuser of others.
In the classic psychoanalytic model, persons with a
paraphilia have failed to complete the normal
developmental process toward sexual adjustment.
Cont…
Biologic Factors.
Several studies have identified abnormal biologic
findings in persons with paraphilias including
Abnormal hormone levels (high androgens),
chromosomal abnormalities, seizures, abnormal EEG
studies, major mental disorders, and an intellectual
disorder.
It is not clear whether these abnormalities are
causally related or incidental to the paraphilia.
The Clinical Presentation and Diagnosis
In DSM-5, for each, but general speaking criteria- A with at
least B or C.(If only A is met-paraphilia not a disorder)
A. Intense and recurrent arousal from their deviant
fantasy for at least 6 months and
B. To either act on the paraphilic impulse or experience
significant distress as a result of the impulse, or
C. Negative consequences / psychosocial impairment
D. Specifiers
Symptom- Sexual activity to dehumanized objects.
Severity- In controlled environment
Course-In full remission no symptoms for at least 5
years
Presentations
Almost all are male
Usually onset is at teens - twenties
Strong sex drive
Fantasize about or hold object during sex
Frequently have more than one paraphilia
Intimacy problems, & personality disturbances
Comorbidities- (mood disorders, Psychotic disorders, social
phobia, GAD, Panic attack, PTSD, ADHD, conduct disorder,
substance use disorder,)
DSM-5 lists 8 paraphilic disorders with explicit diagnostic
criteria because of their threat to others or because are
relatively common.
Exhibitionism
Voyeurism
Frotteurism
Transvestism
Fetishism
Pedophilia
Sexual sadism, and
Sexual masochism
Many others also exist.
Exhibitionism
It is the recurrent urge to expose the genitals to a
stranger or an unsuspecting person.
Sexual excitement occurs in anticipation of the
exposure and orgasm is brought about by masturbation
during or after the event.
Almost all are men exposing themselves to women.
To assert their masculinity by showing their penises
and by watching the victims’ reactions like fright,
surprise, and disgust.
Specify whether
Sexually aroused by exposing genitalia to prepubertal
children, to physically mature individuals or both.
Voyeurism
It is the recurrent preoccupation with fantasies and acts
that involve observing unsuspecting persons who are
naked, engaged in grooming or sexual activity.
Masturbation to orgasm usually accompanies or
follows the event.
The first voyeuristic act usually occurs during
childhood and the paraphilia is most common in men.
Frotteurism
It is usually characterized by a man’s rubbing his
penis against the buttocks or other body parts of a
non consenting fully clothed woman to achieve orgasm.
The acts usually occur in crowded places, particularly in
subways and buses.
Frottage is often their only source of sexual
gratification.
Transvestism
It is described as fantasies and sexual urges to dress
in opposite gender clothing as a means of arousal and
as an adjunct to masturbation or coitus.
More often seen around pubescence or in
adolescence.
DSM specifier with fetishism: aroused by fabrics, material
or garment
With auto gynephilia: aroused by thought or images of self
as female
Fetishism