Professional Documents
Culture Documents
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Objective
2
Industrial hygiene
3
Industrial Hygiene
4
Fundamentals of Industrial Hygiene
Theoretical assessment of
Respect hierarchy exposure
of controls Measurement strategy
Evaluation Monitoring
Evaluation results
Control Report
Basics
IH
5
Fundamentals of Industrial Hygiene
Biological agents
(Ergonomics) • bio hazards
• repetition • fungi
• posture • allergens
• workforce • toxins
6
Chemical Hazards
Dusts
Mists
Fumes
Vapors
Gases
7
Physical Hazards
Noise
Vibrations
Radiation
– Ionizing radiation : Alpha-Beta-Gamma
– Non-ionizing radiation : UV-light, visible light,
infrared, radio waves, microwaves
8
Biological Hazards
Viruses
Fungi or Molds
Bacteria
Plants
Insects
Animals
9
Occupational diseases & IH
10
Occupational health hazards
11
Occupational diseases
Acute poisoning
Occupational cancer
Chronic poison
Interstitial lung disease
Skin disease
Hearing loss
Muscular disorders
Lower-back morbidity and trauma of the spine
…
12
CHEMICAL HAZARDS
Hazardous substances
Examples:
– Chemicals - organic solvents, acids,
pharmaceutical ingredients…
– Dust - metal dust, wood dust, flour…
– Fumes - welding, soldering…
– Fibers - asbestos
14
Hazardous substances can enter the body
inhalation
dermal
ingestion
15
Type of Health Effects
Acute effects –
immediate reaction
Chronic effects –
develop over years
16
Toxicity or poisoning
All substances are toxic, there is not one that is not toxic.
The doses is the difference between a poison and a medicine.
Paracelsus (1493-1541)
Response
Doses
17
Potency of Hazardous Substances
We need xx mg/m3 to
live
18
Describing the hazard
19
Occupational Exposure Limits
20
Variation of exposure with time
22
Who assigns Occupational Exposure Limits?
23
ACGIH TLV’s
24
Examples of OEL’s set by ACGIH (values 2007)
25
Concentration Units
1m
As the proportion of molecules
1m
1 ppm is one part (molecule) in a million
1ppb is one part in a billion
1000 ppb = 1 ppm
26
Setting an OEL – what to consider
Sources of information
– Animal studies
– Pharmaceutical trials
These indicate the lowest active dose, or the dose where
there is no observed adverse effect
27
Setting an OEL – how it is calculated
LAD (mg/kg/day) * BW
OEL = ---------------------------------------------------
V*T*SF*
LAD lowest active dose
BW body weight (50 kg)
V volume inhaled air (10 m 3)
T time, in days, to reach steady state in plasma
SF safety factor
% absorption (assumed = 100%)
28
Typical Notes given with OEL’s
29
Acceptable Surface Limits
30
Acceptable Surface Limits
31
What to do with the OEL and ASL…
32
Evaluate exposure by comparing measured TWA exposure
with OEL
140%
Exposure
130%
exceeds OEL
120% Exposure as % of OEL
110%
100%
90%
TWA as % of OEL
80%
70%
60%
50%
40%
0%
33
Cumulative effect
34
Odor
35
Risk assessment
36
Risk assessment
1. hazard identification
2. dose-response assessment
3. exposure assessment
4. risk characterization
37
Hazardous substances - identification
Processes / activities :
CHA/PHA/PHR (Process Hazard Analysis / Review)
= theoretical evaluation of the
exposure
38
Hazardous substances - identification
Raw materials :
39
Evaluation of risks
Monitoring workplace:
= evaluation exposure at workplace
• Stationary / personal
• Portable / fixed
• Short term / 8 hours
Bio monitoring:
= effects on individual employee
• blood, urine
• long function
• clinical evaluation
40
Hazardous substances - evaluation
Bio
monitoring Stationary monitoring
41
Hazardous substances - evaluation
42
Hazardous substances - identification
– Closed transfer
– Isolators
– Compartments
– Local & overall ventilation
Administrative controls
– Procedures
– Safe behavior analyses
Personal protective equipment
43
Engineering control – prevention hierarchy
Isolator
technology
Closed Transfer
Laminar Flow
Local ventilation
44
Hierarchy of Controls
Elimination
Substitution
Local / General Ventilation
Contained installations
Administrative Controls
Personal Protective Equipment
45
Hazardous substances - control
46
BIOLOGICAL HAZARDS
Biological Hazards
48
Biological hazards
49
Biological hazards
50
Risk prevention
51
Risk reduction
52
Hygiene & individual protection
53
PHYSICAL HAZARDS
NOISE
Noise
56
Noise
57
Effects of noise
58
Hearing impairment and hearing disorders
59
Noise & health surveillance
checks;
keeping health records;
60
Risk prevention
61
Risk assessment …
62
… Risk assessment
63
Risk reduction in practice …
64
… Risk reduction in practice
65
Organizational & administrative noise control
policy;
working methods which generate less noise;
organization of work to reduce noise.
exposed;
appropriate work schedules with adequate rest periods.
66
Hearing protection ?
67
Hearing protection
68
Information and training
69
VIBRATIONS
Vibrations
71
Hand-arm vibrations
72
Whole-body vibrations
73
OEL & action levels
74
Reduction program for exposure to vibrations
75
RADIATION
Radiation
77
Radiation; ionizing & non-ionizing
78
Ionizing radiation (high energy)
79
Non-ionizing radiation (low energy)
80
Control measures for radiation
81