RELATIONSHIP BETWEEN

VENTILATION AND PERFUSION

PRESENTED BY
DR SIMRAN NADEEM
TO
DR MAHNOOR BALOCH
 PREFUSION

Perfusion is the local fluid flow through the capillary

network and extracellular spaces of living tissue.
 VENTILATION

 Ventilation is the process by which 'clean' air (normally

outdoor air) is intentionally provided to a space and stale
air is removed. This may be accomplished by either natural
or mechanical means.
 Ventilation in respiratory physiology is of two types:
 Pulmonary ventilation
 Alveolar ventilation
 PULMONARY VENTILATION

Moving in and out of respiratory tract in a given

unite of time during quiet breathing it is called
minute ventilation or respiratory minute Volume
(RMV)
Pulmonary ventilation is a cyclic process, by which
fresh air enters the lungs and an equal volume of air
leaves the lungs.
 NORMAL VALUE AND CALCULATION

Normal value of pulmonary ventilation is 6,000 ml

(6 L) minute.
 ALVEOLAR VENTILATION

Alveolar ventilation is the amount of air utilized for

gaseous exchange every minute
Alveolar ventilation is different from pulmonary
ventilation.
 NORMAL VALUE AND CALCULATION

Normal value of alveolar ventilation is 4,200 mL (4.2

L) minute.
 IMPORTANCE OF VENTILATION AND PERFUION

 Gas exchange occurs in the

lungs between alveolar air
and the blood of the
pulmonary capillaries. For
effective gas exchange to
occur, alveoli must be
ventilated and perfused.
Ventilation (V) refers to the
flow of air into and out of the
alveoli, while perfusion (Q)
refers to the flow of blood to
alveolar capillaries.
 Ventilation/Perfusion (V/Q) Mismatch

Ventilation-perfusion (V/Q) mismatch occurs when

either the ventilation (airflow) or perfusion (blood
flow) in the lungs is impaired, preventing the lungs
from optimally delivering oxygen to the blood. This
can cause shortness of breath, lightheadedness, or
loss of consciousness, and occur due to chronic lung
diseases.
 CAUSE OF HYPOXEMIA

Hypoxemia is low levels of oxygen in

your blood. It causes symptoms like
headache, difficulty breathing, rapid
heart rate and bluish skin. Many
heart and lung conditions put you at
risk for hypoxemia.