HEPATITIS SEROLOGY

LARAIB KANWAL (202016)

SADIA RAUF (202021)
OBJECTIVES

• How to diagnose Hepatitis C, D & E by using

serology (including specific antibodies for each).
 HEPATITIS C SEROLOGY
ANTI-HCV HCV-RNA INTERPRETATION

Positive Positive Presence of infection.

Positive Negative Resolved hepatitis C/

false positive.

Negative Positive Occult infection

(immunocompromised/
on window period).

Negative Negative Lack of infection.

HEPATITIS D SEROLOGY
 HEPATITIS E SEROLOGY
TEST UTILITY

HEV Antigen Diagnosis of early active infection.

HEV RNA First line diagnosis assay in immunocompromised.

Anti-viral therapy response.

Ig M Anti-HEV First line diagnosis assay in immuno-competent.

Ig G Anti-HEV Past infection.

Vaccine efficacy.