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Drug Study for paracetamol, omeprazole and vitamin B complex

Drug Study for paracetamol, omeprazole and vitamin B complex

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Published by: Michelle Manibale R.N on Aug 12, 2009
Copyright:Attribution Non-commercial

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07/26/2013

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BEFORE:
~ Determine reticulocytecount, hct, Vit.
B
12, iron,folate levels beforebeginning therapy.~ Obtain a sensitivity testhistory beforeadministration~ Avoid I.V. administrationbec. faster systemicelimination will reduceeffectiveness of vitamin.
DURING:
~ Don’t give large doses of vitamin
B
12 routinely; drugis lost through excretion.
~
Don’t mix parenteralpreparation in samesyringe with other drugs.
AFTER:
~ Protect Vit.
B
12 fromlight. Don’t refrigerate or freeze.~ Monitor patient for hypokalemia for first 48hours, as anemia correctitself. Give potassiumsupplements, as needed.
CV:
 peripheralvascular thrombosis,heart failure.
GI:
transientdiarrhea.
Respi:
pulmonaryedema.
Skin:
itching,transitoryexanthema,urticaria.
Other:
anaphylaxis,anaphylactoidreactions withparenteraladministration, pain or burning atinjection site.Perniciousanemia
CONTRA:
~ hypersen-sitive tovitamin B12or cobalt.~ earlyLeber’sdisease
A coenzyme thatstimulatemetabolicfunction and isneeded for cellreplication,hematopoiesis,and nucleoproteinand myelinsynthesis.
VitaminsandMineralsVitamin BcomplexNursing ImplicationsSide EffectsSpecificIndicationMechanismof ActionDoseFrequencyRouteClassificationName of DrugGeneric(Brand)
 
 
BEFORE:
~ Advise parents or caregivers to checkconcentrations of liquidpreparations. Errorshave resulted in seriousliver damage.~ Assess fever; notepresence of associatedsigns (diaphoresis,tachycardia, andmalaise).
DURING:
~ Adults should not takeacetaminophen longer than 10 days andchildren not longer than5 days unless directedby health careprofessional.~ Advise mother or caregiver to take medicationexactly as directed andnot to take more thanthe recommendedamount.
AFTER:
~ Advise patient to consulthealth care professionalif discomfort or fever isnot relieved by routinedoses of this drug or if fever is greater than39.5°C (103°F) or lastslonger than 3 days.
Hema:
hemolyticanemia,
neutropenia,leukopenia,pancytopenia.Hepa:
 jaundice
Metabolic:hypoGGI:
HEPATICFAILURE,HEPATOTOXICITY(overdose)
GU:
renalfailure(highdoses/chronic use).
Derm:
 rash,urticaria.Mild painFever Inhibits thesynthesis of prostaglandins that mayserve asmediators of pain andfever,primarily inthe CNS1.2 mLq 4 hr PRNod
antipyretics,nonopioid analgesics
Acetaminophen(
Paracetamol
)Nursing ImplicationsSide EffectsSpecificIndicationMechanismof ActionDoseFrequencyRouteClassificationName of DrugGeneric(Brand)

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