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Pathophysiology of BPH

Idiopathic Risk Factors: Men 50


Cause y/o and above, Diet,
Obesity, DM, Smoking,
Hormonal fx, and

HYPERPLASIA

Enlarged gland

Accompanied by hypertrophy of the smooth muscle gland

(Benign Prostatic Hyperplasia)

Increase muscular Mechanically adds to


tone at the tissue constricting
bladder neck and theUTI
urethral lumen OBSTRUCTION
proximal urethra

Increase
Urethral
Resistance

Feelings of LUTS Nocturia


incomplete
bladder

Urgency
Daytime
voiding
Associated
frequencyw/ Decline in the
overactive
Urge urinary
Detrusor Acute Urinary
force of the
detrusor
incontinence
decompensate
SYMPTOMS Retention
contractions
urinary systemTURP

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