Professional Documents
Culture Documents
2011
th 5
GROUP
Pathophysiology
Risk factors Transmission Screening Prevention Treatment
DEFINITION
TUBERCULOSIS OR TB (WHICH NOW ABANDONED ABBREVIATIONS ARE TBC) IS AN INFECTIOUS DISEASE CAUSED BY THE BACTERIUM MYCOBACTERIUM TUBERCULOSIS
Classification
Tuberculosis of lung confirmed Pulmonary tuberculosis Tuberculosis in the nervous system Tuberculosis in other organs Tuberculosis millier
chest pain
coughing up blood a productive prolonged
cough for more than three weeks fever chills night sweats
breath malaise
Pathophysiology
The cause of this disease is the bacterium Mycobacterium tuberculosis complex -> because of its size very small -> the TB germs in the spark-organism (droplet nuclei)are inhaled -> can reach the alveoli -> The entry of these TB germs will soon beovercome by a mechanism non specific immunological -> During the early weeks of the infection process -> there is a logarithmic growth TB germs so the body tissues which originally have not beensensitized totuberculinAfter cellular immunity is formed -> the primary focus in the lungtissue is usually experience is perfectly formed the resolution of fibrosis orcalcification after experienced necrosis perkijuan
Risk factors
PERSONS WITH CHRONIC RENAL FAILURE AND DIABETES MILITUS HAVE A RISK FOR DEVELOPING ACTIVE TB .
Transmission
TRANSMISSION OF THE DISEASE BY CONTACT WITH SPUTUM OR INHALING WATER DROPLETS FROM SNEEZING OR COUGHING OF INFECTED PEOPLE GERMS OF TUBERCULOSIS
Screening
MANTOUX TUBERCULIN SKIN TESTS ARE OFTEN USED FOR ROUTINE SCREENING OF HIGH RISK INDIVIDUALS. SPUTUM TEST
Prevention
MANY COUNTRIES USE THE BACILLUS CALMETTE-GURIN (BCG) VACCINE AS PART OF THEIR TB CONTROL PROGRAMMES
Treatment
1. ISONAZID 2. RIFAMPISIN 3. PIRAZINAMID 4. STREPTOMISIN 5. ETAMBUTOL