Pathophysiology of Cellulitis rolling in Diabetes Mellitus Type II

Precipitating factors: 1. Trauma on left foot due to falling in stairs. 2. eating too much sweets and salty food 3. often skips meal

Exhaustion of beta cells pancreas

Predisposing factors: 1. family history of DM 2. obesity 3. Age is 74

Decrease Insulin production/ decrease secretion of insulin in the pancreas

decrease Absorption of glucose by the cell Cell starvation Stimulation of hunger mechanism via hypothalamus

Hunger

Increase glucose level in the blood

Blood Glucose level of 96.8 mg/dL

Increase food intake

POLYPHAGIA

HYPERGLYCEMIA Nerve Demyelinization Urinalysis: 3 RBC present Increase blood viscosity

Kidney filtration mechanism impaired

NEUROPATHY

Blood passes the glomerulus

Glucose passes the glomerulus

Motor: weakness Sensory: loss of pain sensation Autonomic: dry skin, fissures, decrease sympathetic NON-HEALING ULCERS

Hematuria Acidity of urine

GLYCOSURIA

Impaired oxygen perfusion to tissues Urinalysis: 5 pus cells found pyuria

Urethral flora Descending infection occurs UTI

Delayed wound healing

Gangrene

Diabetic foot

Staphylococcus invades the dermis and subcutaneous layer from the traumatized area

Spread of infection and inflammation continues on the connective tissues

Necrosis on connective tissues

Redness, warmth, swelling and skin tightness, pain

Cellulitis

Cyanosis and numbness on affected area

If not managed, spread of infection occurs

Amputation can then be an option to the patient

Legend:

Signs and symptoms

Laboratory results

Pathophysiologic pathway

hunger