bioscientia

Tumor marker

PTH

Parathyroid gland

Pituitary gland

HGH, ACTH, Prolactin

SCC, CEA

Neck/Head region

Breast

CA 15-3, CEA

Calcitonin, Thyreoglobulin

Thyroid

Stomach

CA 72-4, (CEA)

SCC, CEA

Oesophagus

Pancreas

CA 19-9

NSE, Cyfra 21-1, SCC, CEA

Lung/Bronchial

Colon/Rectum

CEA, CA 19-9

Kidney
AFP

Liver Adrenal cortex

M2-PK, TPA
DHEA-S, Cortisol, Aldosterone

CA 19-9, CEA

Gall bladder/Bile duct Pheochromocytoma/ Neuroblastoma Ovarian Bladder Uterus Prostate

Serotonin, 5-Hydroxyacetic-acid (urine)

Carcinoid

Metanephrines (Plasma), *

CA 12-5, CA 72-4

Cyfra21, TPA, NMP22 (urine)

CA 125, CA 19-9

PSA PCA3

Cervix Lymphatic myeloid system

SCC, CEA
Paraproteins, Bence-JonesProteins, # Ostase, Desoxypyridinoline (urine)

AFP, HCG, Placenta-AP, LDH

Testicular

Protein S-100

Skin/Melanoma

Bone

* Catecholamines (urine), vanillylmandelic acid, homovanillic acid, NSE # Thymidine kinase, 2-Microglobulin

p.t.o.

05/2008

bei

Tumor adrenal cortex bile duct/gall bladder bladder cancer breast cancer

Turmor marker or typical metabolite DHEA-S, Cortisol, Aldosterone CA 19-9, CEA Cyfra 21-1, TPA, NMP22 in urine CEA, CA 15-3, HER-2/neu (serum, tissue) uPA/PAI-1 (Gewebe) ER und PR (tissue) NSE, Cyfra 21-1 SCC, Cyfra 21-1, CEA Cyfra 21-1, CEA Cyfra 21-1, CEA Serotonin, 5-hydroxyindolacetic acid in urine SCC, CEA -hCG
CEA

Tumor marker 2nd choice

bronchial carcinoma oat cell carcinoma squamous cell carcinoma adenocarcinoma magnocellular carcinoma carcinoid cervix cancer chorio carcinoma (Cystic mole) colo-rectal carcinoma gastric carcinoma hepatocellular carcinoma hypophyseal tumor lymphatic and myeloid leukemias malignant tumors in the head and neck region melanoma nephrocarcinoma (hypernephroma) neuroendocrine tumor (APUD cell tumor) oesophageal carcinoma osteosarcoma, bone metastases ovarian cancer epithelial mucin pancreatic cancer pheochromocytoma/ paraganglioma

ACTH, Calcitonin, TPA TPA

CA 19-9 CEA, CA 19-9, CA 50

CA 72-4 AFP HGH, ACTH, Prolactin Paraproteins, 2-Microglobulin, Thymidine kinase, Neopterin SCC, CEA Protein S-100 M2-PK, TPA NSE, Chromogranin A SCC, CEA Ostase, (Desoxy-)Pyridinolin in urine CA 125, CASA CA 125, CA 72-4 CA 19-9 Metanephrines in plasma, Catecholamines in urine,

FSH, LH, TSH

CEA

CA 125, CA 50 homovanillic acid in urine, Metanephrines in urine, vanillylmandelic acid in urine, NSE, Chromogranin A

prostatic cancer testicular cancer germinal tumor seminoma thyroid cancer papillary, follicular medullary (C cell carcinoma) uterus carcinoma Zollinger-Ellison-syndrome (Gastrinoma)

PSA, free PSA, PCA3 in urine AFP , -hCG, LDH Placenta-AP , AFP , -hCG, LDH Thyreoglobulin Calcitonin (possibly after Pentagastrin), CEA CA 125, CA 19-9 Gastrin TPA, CEA

NSE