<http://www.sciencedirect.com/> <http://www.sciencedirect.com/> * ScienceDirect * Scopus <http://www.scopus.com> * Applications <http://www.applications.sciverse.com/action/userhome> * Register <https://www.sciencedirect.com/science?_ob=RegistrationURL&_method=display&_ type=guest&_returnURL=http%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Flogin&_acct =C000228598&_version=1&_userid=10&md5=7a418779018b97e81107a337f97128c0> * Login <javascript:LoginBox.

flipLogin('loginBox',null);> * Go to SciVal Suite <http://www.scival.com> Username: Password: Remember me | Not Registered? <https://www.sciencedirect.com/science?_ob=RegistrationURL&_method=display&_type =guest&_returnURL=http%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Flogin&_acct=C00 0228598&_version=1&_userid=10&md5=7a418779018b97e81107a337f97128c0> Forgotten your username or password? <http://www.sciencedirect.com/science?_ob=ReminderURL&_method=display&_acct=C000 228598&_version=1&_userid=10&md5=47dd38b07cdc1f0f4c3ce0e1c7967215> Go to Athens / Institution login </science?_ob=FederationURL&_method=display&_type=f&_acct=C000228598&_version=1& _userid=10&md5=4588277742fa8648d3a754e394556c55> Remote access activation <http://www.sciencedirect.com/science/activateaccess> * Home <http://www.sciencedirect.com> * Publications <http://www.sciencedirect.com/science/browse> * Search <http://www.sciencedirect.com/science?_ob=MiamiSearchURL&_method=requestForm &_btn=Y&_zone=TopNavBar&_origin=article&_acct=C000228598&_version=1&_urlVersion= 1&_userid=10&md5=39b3eb2d7921081816953b8c126d4d1e> * My settings <http://www.sciencedirect.com/science?_ob=UserSubscriptionURL&_method=begin& _btn=Y&_zone=TopNavBar&_origin=article&_acct=C000228598&_version=1&_urlVersion=1 &_userid=10&md5=7028052249c85a73d258a77d39038b36> * My alerts <http://www.sciencedirect.com/science?_ob=MiamiSDIURL&_method=listAlerts&_bt n=Y&_zone=TopNavBar&_origin=article&_acct=C000228598&_version=1&_urlVersion=0&_u serid=10&md5=5713335a2ad9c5aa94441b399aa83b5e> * Shopping cart <http://www.sciencedirect.com/science?_ob=ShoppingCartURL&_method=display&_z one=TopNavBar&_origin=article&_acct=C000228598&_version=1&_userid=10&md5=970884c 23c786181ae7d8e5cc2a321ad> * Help <http://www.sciencedirect.com/science?_ob=HelpURL&_file=browse_open_doc.htm& _btn=Y&_zone=TopNavBar&_origin=article&_acct=C000228598&_version=1&_urlVersion=0 &_userid=10&md5=00ae555385dab9ff9d6838b8a122fa9b> <http://info.sciencedirect.com/using/access_article_display/guest/>

* * Export citation </science?_ob=DownloadURL&_method=confirm&_eidkey=1-s2.0-S0090825810004051&c ount=1&_docType=FLA&zone=toolbar&_acct=C000228598&_version=1&_userid=10&md5=fac7 eee07892bfcb5903a3d53f4ccd63> * Purchase </science?_ob=ShoppingCartURL&_method=add&_eid=1-s2.0-S0090825810004051&orig inContentFamily=serial&_origin=article&_acct=C000228598&_version=1&_userid=10&_t s=1361684010&md5=fbf6c4a0526ef2fe20dc2c766d5d56f6> * More options... <#> o Email article </science?_ob=EmailFriendURL&_method=gatherInfo&refSource=abst&count=1&_ eidkey=1-s2.0-S0090825810004051&_acct=C000228598&_version=1&_userid=10&md5=edfdc d83ef8c04626f62671afdb130e4> o Signed up for journal alerts [remove </science?_ob=PublicationURL&newIssueAlert=2&_cid=272587&_pubType=J&_aut h=y&originContentFamily=serial&_pii=S0090825810004051&_acct=C000228598&_version= 1&_urlVersion=0&_userid=10&md5=ec445f627e542d1f9774832a143296ed>] Alert me about new articles in this journal </science?_ob=PublicationURL&newIssueAlert=2&_cid=272587&_pubType=J&_aut h=y&originContentFamily=serial&_pii=S0090825810004051&_acct=C000228598&_version= 1&_urlVersion=0&_userid=10&md5=ec445f627e542d1f9774832a143296ed>

Failure Your selection(s) could not be saved due to an internal error. Please try again. Search All fields Author Advanced search <http://www.sciencedirect.com/science?_ob=MiamiSearchURL&_method=requestForm&_bt n=Y&_acct=C000228598&_version=1&_urlVersion=1&_userid=10&md5=18a1082f74248d90d46 5ee65804fd7db> Journal/Book title Volume Issue Page Search tips <http://www.sciencedirect.com/science?_ob=HelpURL&_origin=srch_form&_zone=TopNav Bar&_file=qs_tips.htm&_acct=C000228598&_version=1&_urlVersion=0&_userid=10&md5=f 15db24b506e33b76c987597749c8123> Show thumbnails in outline * Abstract <http://www.sciencedirect.com/science/article/pii/S0090825810004051> *

/Objective/ <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * /Methods/ <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * /Results/ <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * /Conclusions/ <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Keywords <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Introduction <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Materials and methods <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Cohort study design <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Cervical cytology and HPV genotyping <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Antioxidant nutrient study sample <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Diet questionnaire <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Statistical analyses <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Results <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Table 1 <#tbl1> * Table 2 <#tbl2> * Table 3 <#tbl3> * Table 4 <#tbl4> * Discussion <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Conflict of interest statement <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Acknowledgments <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * Appendix A. Supplementary data <http://www.sciencedirect.com/science/article/pii/S0090825810004051> * e-component0005

<http://www.sciencedirect.com/science/article/pii/S0090825810004051> * References <http://www.sciencedirect.com/science/article/pii/S0090825810004051> Gynecologic Oncology <http://www.sciencedirect.com/science/journal/00908258> Volume 118, Issue 3 <http://www.sciencedirect.com/science/journal/00908258/118/3>, September 2010, Pages 289294 Cover image <http://www.sciencedirect.com/science/journal/00908258/118/3> Dietary consumption of antioxidant nutrients and risk of incident cervical intraepithelial neoplasia * * * * * * Erin M. Siegel <#>^a <#aff1>^, ^b <#aff2>, Jason L. Salemi <#>^b <#aff2>, Luisa L. Villa <#>^c <#aff3>, Alex Ferenczy <#>^d <#aff4>, Eduardo L. Franco <#>^d <#aff4>^, ^e <#aff5>, Anna R. Giuliano <#>^a <#aff1>^, ^b <#aff2>^, Corresponding author contact information <#cor1>^, E-mail the corresponding author <mailto:Anna.Giuliano@moffitt.org>

* ^a Risk Assessment, Detection and Intervention Program, Moffitt Cancer Center, Tampa, FL, USA * ^b Department of Epidemiology & Biostatistics, College of Public Health, University of South Florida, Tampa, FL, USA * ^c Ludwig Institute for Cancer Research, So Paolo, Brazil * ^d Department of Oncology, McGill University, Montreal, Quebec, Canada * ^e Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada ^Corresponding author contact information <#bcor1> Corresponding author. Risk Assessment Detection and Intervention Program, Moffitt Cancer Center, 12902 Magnolia Dr, Tampa, FL 33612, USA. Fax: + 1 813 745 6507. Received 14 December 2009 Available online 18 June 2010 * http://dx.doi.org/10.1016/j.ygyno.2010.05.022, How to Cite or Link Using DOI <http://www.sciencedirect.com/science/help/doi.htm> * Permissions & Reprints </science?_ob=RedirectURL&_method=outwardLink&_partnerName=936&_eid=1-s2.0-S 0090825810004051&_pii=S0090825810004051&_origin=article&_zone=art_page&_targetUR L=https%3A%2F%2Fs100.copyright.com%2FAppDispatchServlet%3FpublisherName%3DELS%26 contentID%3DS0090825810004051%26orderBeanReset%3Dtrue&_acct=C000228598&_version= 1&_userid=10&md5=af5c30164cdec82dbc5dbf51bacbba80> View full text <http://www.sciencedirect.com/science/article/pii/S0090825810004051> Purchase $39.95 </science?_ob=ShoppingCartURL&_method=add&_eid=1-s2.0-S0090825810004051&_acct=C 000228598&_version=1&_userid=10&_ts=1360870443&md5=bc6d442c21a57108172336ac17f50 054>

Introduction Materials and methods Results Discussion Conflict of interest statement Acknowledgments Appendix A. Supplementary data References -----------------------------------------------------------------------Abstract /Objective/ Women with human papillomavirus (HPV) infections are at risk for developing squamous intraepithelial lesions (SIL) of the cervix; however, other factors are required for infections to progress to SIL. We hypothesize that consumption of fruits and vegetables high in antioxidant nutrients may prevent, in part, the development of HPV-associated SIL. /Methods/ This study is a nested case-control study of 265 HPV-positive women (93 SIL cases and 172 cytologically normal controls) in the LudwigMcGill Cohort Study, So Paulo, Brazil. Diet was assessed by a self-administered food frequency questionnaire. The association between food and nutrient intake of antioxidants and incident SIL was determined by logistic regression and multinomial regression when comparing LSIL and HSILs. /Results/ Higher reported consumption of papaya was inversely associated with risk of SIL (/p/ trend = 0.01) and strongest for 1 time/week (adjusted odds ratios (AORs) = 0.19; 95%CI, 0.080.49). Risk of SIL was reduced among women reporting consumption of oranges 1 time/week (AOR = 0.32; 95%CI, 0.120.87; /p/-trend = 0.02). Nutrient intakes of //-cryptoxanthin and -crotene were marginally protective against SIL.

/Conclusions/ Frequent consumption of fruits high in antioxidant nutrients appears to be associated with reduced risk of incident SIL among Brazilian women. Keywords * * * * * Cervical cancer; Cervical intraepithelial neoplasia; Human papillomavirus; Diet; Antioxidant nutrient

-----------------------------------------------------------------------Figures and tables from this article: Table 1. Characteristics of cases with any-grade squamous intraepithelial lesion (SIL) and frequency-matched controls. View Within Article </science/article/pii/S0090825810004051> Table 2. Frequency of food consumption and energy-adjusted mean (SD) values of nutrient intake for cases of any-grade squamous intraepithelial lesion (SIL) and controls. View Within Article </science/article/pii/S0090825810004051> Table 3. Association between consumption of select fruits and vegetables and incident squamous intraepithelial lesion (SIL) diagnosis among HPV positive women^a <#tblfn6>: Overall and by SIL diagnosis. View Within Article </science/article/pii/S0090825810004051> Table 4. Association between energy-adjusted intake of carotenoids and antioxidant vitamins and incident squamous intraepithelial lesion (SIL) diagnosis among HPV positive women^a <#tblfn10>: Overall and by SIL diagnosis. View Within Article </science/article/pii/S0090825810004051> ^Corresponding author contact information <#bcor1> Corresponding author. Risk Assessment Detection and Intervention Program, Moffitt Cancer Center, 12902 Magnolia Dr, Tampa, FL 33612, USA. Fax: + 1 813 745 6507. Copyright 2010 Elsevier Inc. All rights reserved. Bibliographic information Citing and related articles Related articles

1. 1. Chapter 5: Updating the natural history of HPV and anogenital cancer </science/article/pii/S0264410X06007328> 2. 2006, Vaccine 3. Show more information Close 1. Anna-Barbara Moscicki , Mark Schiffman , Susanne Kjaer , Luisa L. Villa 2. Chapter 5: Updating the natural history of HPV and anogenital cancer 3. Vaccine, Volume 24, Supplement 3, 21 August 2006, Pages S42S51 4. Original Research Article * PDF (497 K) </science?_ob=MiamiImageURL&_cid=271205&_user=10&_pii=S0264410X0 6007328&_check=y&_origin=article&_zone=rightPane&_coverDate=2006-08-21&_piiSugge stedFrom=S0264410X06007328&panel=citeRelatedArt&wchp=dGLzVBA-zSkWz&md5=95276a7a4 cc4b276f08b4c98a92c66b1&pid=1-s2.0-S0264410X06007328-main.pdf > 2. 1. A pilot casecontrol association study of cytokine polymorphisms in Brazilian women presenting with HPV-related cervical lesions </science/article/pii/S0301211508001486> 2. 2008, European Journal of Obstetrics &amp; Gynecology and Reproductive Biology 3. Show more information Close 1. Ana Paula M. Fernandes , Maria Alice G. Gonalves , Renata T. Simes , Celso T. Mendes-Junior , Geraldo Duarte , Eduardo A. Donadi 2. A pilot casecontrol association study of cytokine polymorphisms in Brazilian women presenting with HPV-related cervical lesions 3. European Journal of Obstetrics &amp; Gynecology and Reproductive Biology, Volume 140, Issue 2, October 2008, Pages 241244 4. Original Research Article * PDF (113 K) </science?_ob=MiamiImageURL&_cid=271236&_user=10&_pii=S030121150 8001486&_check=y&_origin=article&_zone=rightPane&_coverDate=2008-10-31&_piiSugge stedFrom=S0301211508001486&panel=citeRelatedArt&wchp=dGLzVBA-zSkWz&md5=fb759e547 cbbbd968f89a6ffcf15895c&pid=1-s2.0-S0301211508001486-main.pdf > 3. 1. CHAPTER 17 Cervical Dysplasia and Cancer </science/article/pii/B9780443066399500253> 2. 2005, Women's Health in Complementary and Integrative Medicine A Clinical Guide 3. Show more information Close 1. Tieraona Low Dog 2. CHAPTER 17 Cervical Dysplasia and Cancer 3. Women's Health in Complementary and Integrative Medicine A Clinical Guide, 2005, Pages 278292 *

PDF (274 K) </science?_ob=MiamiImageURL&_cid=277974&_user=10&_pii=B978044306 6399500253&_check=y&_origin=article&_zone=rightPane&_coverDate=2005-12-31&_piiSu ggestedFrom=B9780443066399500253&panel=citeRelatedArt&wchp=dGLzVBA-zSkWz&md5=aad 08248ec43a3059c6556381662c295&pid=3-s2.0-B9780443066399500253-main.pdf > 4. View more articles </science?_ob=RelatedArtURL&_pii=S0090825810004051&_orig=article&_zone=right Pane&panel=citeRelatedArt&_mlktType=NoRefwork&_isSubscribed=N&_acct=C000228598&_ version=1&_userid=10&md5=28556bab571b73a2f9efa2451a04c6fc> Cited by in Scopus (5) </science?_ob=RedirectURL&_method=outwardLink&_partnerName=656&_eid=1-s2.0-S 0090825810004051&_pii=S0090825810004051&_origin=article&_zone=art_page&_targetUR L=http%3A%2F%2Fwww.scopus.com%2Finward%2Fcitedby.url%3Feid%3D2-s2.0-77955558320% 26partnerID%3D10%26rel%3DR3.0.0%26md5%3D4716b75970863d46bc4080424714b90b&_acct=C 000228598&_version=1&_userid=10&md5=77eca48205f51b23fa9844f659f78a93> Related reference work articles 1. No articles found. Applications and tools Gadget timed out while loading [Share] Share * <javascript:void(0);> * <javascript:void(0);> * <javascript:void(0);> <javascript:shindig.container.getGadget(2).closeGadget();> + Show more applications Show fewer applications Add apps Help <javascript:openHelpPage(sciverseObj.contextInfo.pageType); > Workspace # No content has been selected. Elsevier homepage (opens in a new window) <http://www.elsevier.com> * About ScienceDirect <http://www.info.sciverse.com/sciencedirect?utm_source=sciencedirect&utm_med ium=link&utm_campaign=aboutsd>

* About Elsevier <http://www.elsevier.com/?utm_source=sciencedirect&utm_medium=link&utm_campa ign=aboutelsevier> * Contact and support <http://www.sciencedirect.com/science/contactus> * Information for advertisers <http://www.elsevierscitech.com/forms/sd/form.html?utm_source=sciencedirect& utm_medium=link&utm_campaign=advert> * Terms and conditions <http://www.elsevier.com/locate/termsandconditions?utm_source=sciencedirect& utm_medium=link&utm_campaign=terms> * Privacy policy <http://www.elsevier.com/privacypolicy?utm_source=sciencedirect&utm_medium=l ink&utm_campaign=privacy> Copyright 2013 Elsevier B.V. <http://www.elsevier.com> All rights reserved. SciVerse is a registered trademark of Elsevier Properties S.A., used under license. ScienceDirect is a registered trademark of Elsevier B.V. Close <#> ScienceDirect article suggestions ScienceDirect * Related articles <#> These articles have key terms similar to those in the article you downloaded. Learn more <#> Do not show again <#> [Entitle Gadget] Entitle Gadget * <javascript:void(0);> * <javascript:void(0);> <javascript:shindig.container.getGadget(3).closeGadget();>