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Drug Calculations in Paediatrics

Ann McDermott, Senior sister PICU Mark Darowski, Consultant PICU

Aims of this presentation • To make you familiar with – Units of measurement – The standard drug calculation formulae – Converting • Rates into dosages (i.e.e. x microg/kg/min = y ml/hr) . x ml = y microg/kg/min) • Dosages into rates (i.

Units • 1 gram (g) = 1000 miligrams(mg) • 1 mg = 1000 micrograms(microg) • 1 microgram = 1000 nanograms (nanog) .

g. hour 150mg phenytoin is prescribed (what you want) you have 250mg (what you’ve got) in 5 ml (what it’s in) 150 x 5 = 3ml is the volume you need to give 250 .Standard formula What you want x What it’s in What you’ve got All of the values must be in the same unit of measure e. mg. mls.

3. Convert to same unit of measure Divide by the volume of diluent Multiply by the rate 1. I am giving z microgram/hr I am giving u microgram/kg/hr I am giving w microgram/kg/min 4. 4. Divide by the patients weight (divide by 60 for minutes) . 2.Rates to dosages 1. 5. I have y microgram/ml 3. I have x microgram 2. 5.

Example Adrenaline 10mg in 100ml running at 4ml/hr in a 70 kg patient.7 microg/kg/hr My patient is receiving 5.7 ÷ 60 = 0.09 microg/kg/min . How many microg/kg/min is the patient getting? 1. 4. 5. 2. I have 10 mg = 10000 microg I have 10000 ÷ 100 = 100 microg/ml I am giving 4 x 100 = 400 microg/hr I am giving 400 ÷ 70 = 5. 3.

Doses to rates Amount of drug required x weight x (60) Divided by microgram/ml of drug = ml/hr .

0.4 ml/hr .Example 2 Patient of 70kg prescribed adrenaline at 0.2 x 70 x 60 = 840 microg/hr = what you want 10mg in 100ml = 100 microg/ml = what you’ve got What you want = What you’ve got 840 100 = 8.2 microgram/kg/min.

Safe practice and documentation • If unsure – say so • Safety checks – do long hand • Labelling of syringes and lines • Two nurses to: – Check pump set-up – Alter infusion rates – Sign chart and label .