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Mange in dogs generally first presents with small isolated red patches or pustules on the dogs skin. Minor cases generally appear first around the face and eyes of the dog, and also on the forelimbs and paws. The problem begins when the dog becomes sensitive to the mite infestation, as the immune system cannot keep the infestation under control. Mange in dogs often occurs when the dog has an undeveloped immune system, or is under intense stress. Small isolated infections of the mites are considered normal, especially in puppies. When a vet considers the infestation or reaction bad enough, they will prescribe ointment or perhaps an anti-parasitic dip.